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==Epidemiology and demographics==
==Epidemiology and demographics==
Since 1996, fewer than 50 confirmed cases were reported in the United States each year. Many more cases may occur that are not correctly diagnosed or reported.<ref name="urlDisease Listing, Psittacosis, Technical Information | CDC Bacterial, Mycotic Diseases">{{cite web |url=http://www.cdc.gov/ncidod/dbmd/diseaseinfo/psittacosis_t.htm |title=Disease Listing, Psittacosis, Technical Information &#124; CDC Bacterial, Mycotic Diseases |format= |work= |accessdate=}}</ref>. In the united states, the incidence of psittacosis is 0.01 per 100,000 persons. The prevalence and incidence of psittacosis does not vary by gender neither is there a racial predilection for psittacosis has it has been identified in all parts of the world icluding, Africa, china, Europe and the United states.


==Risk factors==
==Risk factors==

Revision as of 15:20, 27 June 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Psittacosis zoonotic infectious disease caused by a bacterium called Chlamydophila psittaci (formerly Chlamydia psittaci) and contracted not only from parrots, such as macaws, cockatiels and budgerigars, but also from pigeons, sparrows, ducks, hens, sea gulls and many other species of bird. The incidence of infection in canaries and finches is believed to be lower than in psittacine birds. As a systemic zoonotic infection with protean clinical features, the major risk factor is exposure to birds. Hence, bird owners, veterinarians, those involved with breeding and selling birds, and commercial poultry processors are most at risk. Patients typically present with 1 week of fevers, headache, myalgias, and a nonproductive cough. Although pneumonia is the most common manifestation, all organ systems can be involved. Serology remains the mainstay of diagnosis; however, polymerase chain reaction techniques offer a rapid and specific alternative. Doxycycline is the treatment of choice.

Historical perspective

The word psittacosis is derived from the Greek work 'Psittakos', which means parrot. Psittacosis infects psittacines (parrots, parakeets, cockatoos). 'Ornithosis' is a term used if it infects other types of birds. It is assumed that the origin of psittacosis is in South America, where the rain forests are populated with many species of psittacine birds. Aboriginal tribes were fond of these birds and used their feathers as parts of their ceremonial clothing. Other psittacine birds were kept as pets in aboriginal villages. [1]

Classification

C psittaci may be classified into eight serovars according to variation in the major outer membrane protein (MOMP): serovar A to F, WC and M56.[2]

Pathophysiology

The major risk factor for acquiring psittacosis is exposure to birds. Transmission can occur either by inhalation of aerosolized organisms in form of dried feces or respiratory secretions or by direct contact with birds.

Causes

Psittacosis is caused by the organism Chlamydia psittaci. Chlamydia is understood to be a Gram-negative bacterium belonging to the genus Chlamydia or Chlamydophila in the family of Chlamydiaceae together with Parachlamydiaceae, Waddliaceae and Simkaniaceae in the order Chlamydiales, class and phylum Chlamydiae. Chlamydiales are obligate intracellular infectious agents in eukaryotic cells characterized by a unique developmental replication cycle.[3]

Differential diagnosis

Psittacosis must be differentiated from other diseases that cause atypical pneumonia, febrile illness without localizing signs and extrapulmonary manifestations such as gastroenteritis, hepatitis, meningitis, or encephalitis. The three main diseases to differentiate psittacosis from are Chlamydia pneumoniae, Mycoplasma pneumoniae, and Legionella infection as they tend to have similar clinical manifestations which can only be differentiated by taking appropriate histories and laboratpory investigations. There are other conditions to watch out for which may also present similar to psittacosis.

Epidemiology and demographics

Since 1996, fewer than 50 confirmed cases were reported in the United States each year. Many more cases may occur that are not correctly diagnosed or reported.[4]. In the united states, the incidence of psittacosis is 0.01 per 100,000 persons. The prevalence and incidence of psittacosis does not vary by gender neither is there a racial predilection for psittacosis has it has been identified in all parts of the world icluding, Africa, china, Europe and the United states.

Risk factors

Screening

Natural history, complications and prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

MRI

Echocardiography or ultrasound

Other imaging findings

Other diagnostic studies

Treatment

Medical therapy

Surgery

Primary prevention

Secondary prevention

References

  1. Wehrle B, Chiquet M (1990). "Tenascin is accumulated along developing peripheral nerves and allows neurite outgrowth in vitro". Development. 110 (2): 401–15. PMID 1723942.
  2. Vanrompay D, Butaye P, Sayada C, Ducatelle R, Haesebrouck F (1997). "Characterization of avian Chlamydia psittaci strains using omp1 restriction mapping and serovar-specific monoclonal antibodies". Res Microbiol. 148 (4): 327–33. doi:10.1016/S0923-2508(97)81588-4. PMID 9765811.
  3. de Rossi G, Focacci C (1979). "Early detection of craniosynostosis by 99mTc-pyrophosphate bone scanning". Radiol Diagn (Berl). 20 (3): 405–9. PMID 229510.
  4. "Disease Listing, Psittacosis, Technical Information | CDC Bacterial, Mycotic Diseases".


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