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Differentiating protein energy malnutrition from other micronutrient deficiency
==Differentiating protein energy malnutrition from other micronutrient deficiency==
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Revision as of 15:18, 4 August 2017


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omodamola Aje B.Sc, M.D. [2]

Overview

As protein energy malnutrition manifests in a variety of clinical forms, differentiation must be established in accordance with the particular subtype. Kwashiorkor must be differentiated from other diseases that cause failure to thrive, wasting, edema, skin and hair changes such as congenital heart diseases and micronutrient deficiency. In contrast, marasmus must be differentiated from other diseases that cause generalised wasting, such as vitamin A , iron, iodine, and zinc deficiencies.

Differentiating Protein energy malnutrition from other Diseases

Differentiating kwashiorkor from marasmus[1]

Distinguishing Features Kwashiorkor Marasmus
Cause Deficiency of protein in the diet of child Deficiency of protein as well as energy nutrients (that is carbohydrates and fats) in the diet
Age Occurs in children in the age group 1-5 years Typically occurs in children below the age of 1 year
Association More common in villages where there is small gap period between successive pregnancies More common in towns and cities where breast-feeding in discontinued quite early
Edema Presence of edema Absence of edema
Muscles Wasting of muscles Wasting of muscles is quite evident. The child is reduced to skin and bones
Skin changes Dermatitis and Hyperpigmentation noticed Dry and atrophic skin but no changes in color
Serum cortisol Decreased/Normal Increased
Fasting blood glucose Decreased Decreased
Growth retardation Mildly retarded in growth Severely retarded in growth
Facial appearance Moon-like face Elderly man face
Abdomen Protuded Shrunken
Vitamin deficiency Present Present
Weight 60-80% of normal weight for age <60% of normal weight for age

Differentiating protein energy malnutrition from other micronutrient deficiency

Kwashiorkor
Marasmus
Vitamin A deficiency
Iron deficiency
Iodine deficiency
Congenital heart disease
Dehydration
Sepsis
Shigella and campylobacter

References

  1. Müller O, Krawinkel M (2005). "Malnutrition and health in developing countries". CMAJ. 173 (3): 279–86. doi:10.1503/cmaj.050342. PMC 1180662. PMID 16076825.

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