Primary sclerosing cholangitis: Difference between revisions

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__NOTOC__
{{DiseaseDisorder infobox |
{{DiseaseDisorder infobox |
   Name        = Primary sclerosing cholangitis |
   Name        = Primary sclerosing cholangitis |
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'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''


{{CMG}}
{{CMG}}; {{AE}}{{DN}}
==Overview==


==Signs and symptoms==
{{SK}} PSC; primary sclerosing cholangitis
==[[Primary sclerosing cholangitis overview|Overview]]==


==Diagnosis==
==[[Primary sclerosing cholangitis historical perspective|Historical Perspective]]==


==Etiology==
==[[Primary sclerosing cholangitis classification|Classification]]==


==Pathophysiology==
==[[Primary sclerosing cholangitis pathophysiology|Pathophysiology]]==


==Epidemiology==
==[[Primary sclerosing cholangitis causes|Causes]]==


==Screening==
==[[Primary sclerosing cholangitis differential diagnosis|Differentiating Primary sclerosing cholangitis from other Diseases]]==
PSC is associated with [[cholangiocarcinoma]], which are tumors involving the biliary tree.  Screening for cholangiocarcinoma in patients with PSC is encouraged, but there is no general consensus on the modality and interval of choice.


==Therapy==
==[[Primary sclerosing cholangitis epidemiology and demographics|Epidemiology and Demographics]]==
Standard treatment includes [[ursodiol]], a bile acid naturally produced by the liver, which has been shown to lower elevated liver enzyme numbers in people with PSC, but has not yet been proven effective at prolonging the life of the liver.  Treatment also includes medication to relieve itching ([[antipruritic]]s) and bile acid sequesterants (cholestyramine), [[antibiotic]]s to treat infections, and [[vitamin]] supplements, as people with PSC are often deficient in [[vitamin A]], [[vitamin D]], and [[vitamin K]].


In some cases, ERCP, which may involve stenting of the common bile duct, may be necessary in order to open major blockages (dominant strictures).
==[[Primary sclerosing cholangitis risk factors|Risk Factors]]==


[[Liver transplantation]] (including live transplants whereby a portion of a living donor is given to the recipient) is an option if the liver begins to fail.
==[[Primary sclerosing cholangitis screening|Screening]]==
 
==[[Primary sclerosing cholangitis natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
 
==[[Primary sclerosing cholangitis diagnosis|Diagnosis]]==
[[Primary sclerosing cholangitis history and symptoms|History and Symptoms]] | [[Primary sclerosing cholangitis physical examination|Physical Examination]] | [[Primary sclerosing cholangitis laboratory findings|Laboratory Findings]] | [[Primary sclerosing cholangitis electrocardiogram|Electrocardiogram]] | [[Primary sclerosing cholangitis x ray|X Ray]] | [[Primary sclerosing cholangitis CT|CT]] | [[Primary sclerosing cholangitis MRI|MRI]] | [[Primary sclerosing cholangitis ultrasound|Ultrasound]] | [[Primary sclerosing cholangitis other imaging findings|Other Imaging Findings]] | [[Primary sclerosing cholangitis other diagnostic studies|Other Diagnostic Studies]]
 
==Treatment==
[[Primary sclerosing cholangitis medical therapy|Medical Therapy]] | [[Primary sclerosing cholangitis surgery|Surgery]] | [[Primary sclerosing cholangitis primary prevention|Primary Prevention]] | [[Primary sclerosing cholangitis secondary prevention|Secondary Prevention]] | [[Primary sclerosing cholangitis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Primary sclerosing cholangitis future or investigational therapies|Future or Investigational Therapies]]
 
==Case Studies==
 
[[Primary sclerosing cholangitis case study one|Case #1]]


== See also ==
== See also ==
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* [[Alagille syndrome]]
* [[Alagille syndrome]]
* [[Progressive familial intrahepatic cholestasis]]
* [[Progressive familial intrahepatic cholestasis]]
* Walter Payton (died of primary sclerosing cholangitis)


== External links ==
== External links ==
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{{Gastroenterology}}
{{Gastroenterology}}


[[Category:Autoimmune diseases]]
[[Category:Gastroenterology]]
[[Category:Gastroenterology]]
[[Category:Hepatology]]
[[Category:Hepatology]]
[[Category:Inflammations]]


[[de:Cholangitis]]
[[de:Cholangitis]]

Latest revision as of 18:16, 12 December 2016

Template:DiseaseDisorder infobox

Primary sclerosing cholangitis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Primary sclerosing cholangitis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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For patient information click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]

Synonyms and keywords: PSC; primary sclerosing cholangitis

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Primary sclerosing cholangitis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X Ray | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

See also

External links

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de:Cholangitis sv:Primär skleroserande kolangit


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