Primary hyperaldosteronism differential diagnosis
Overview
Differebtiating Conn's Syndrome From Other Diseases
Conn's syndrome should be differentiated from other diseases causing hypertension and hypokalemia for example:
- Renal artery stenosis
- Cushing's syndrome
- Congenital adrenal hyperplasia (CAH)
- 17 alpha hydroxylase deficiency
- 11 beta hydroxylase deficiency
- Liddle's syndrome
- Diuretic use
- Licorice ingestion
- Renin-secreting tumors
| Hypertension and Hypokalemia | |||||||||||||||||||||||||||||||||||||||||||||||
| Plasma renin activity | |||||||||||||||||||||||||||||||||||||||||||||||
| Normal or High | Suppressed | ||||||||||||||||||||||||||||||||||||||||||||||
| Consider other diagnosis | Urinary aldosterone | ||||||||||||||||||||||||||||||||||||||||||||||
| Elevated | Normal | Low | |||||||||||||||||||||||||||||||||||||||||||||
| Conn's syndrome (Primary aldosteronism) | Profound K+ depletion | • 17 alpha hydroxylase deficiency • 11 beta hydroxylase deficiency • Liddle's syndrome • Licorice ingestion • Deoxycortisone producing tumor | |||||||||||||||||||||||||||||||||||||||||||||