Primary biliary cirrhosis MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]

Overview

Abdominal MRI may be helpful in the diagnosis of primary biliary cirrhosis. Findings on MRI suggestive of primary biliary cirrhosis are parenchymal lace-like fibrosis and periportal halo sign.

MRI

  • Abdominal MRI may be helpful in the diagnosis of primary biliary cirrhosis. Findings on MRI suggestive of primary biliary cirrhosis are parenchymal lace-like fibrosis and periportal halo sign. Other characteristic features include:[1][2][3]
    • Irregularly appearing regenerative nodules on the hepatic surface
    • Hyperintense periportal region
    • Segmental hypertrophy of the caudate lobe
    • Regional lymphadenopathy
    • Splenomegaly


Case courtesy of Radswiki, Radiopaedia.org, rID: 11816

References

  1. Kumagi T, Heathcote EJ (2008). "Primary biliary cirrhosis". Orphanet J Rare Dis. 3: 1. doi:10.1186/1750-1172-3-1. PMC 2266722. PMID 18215315.
  2. Purohit T, Cappell MS (2015). "Primary biliary cirrhosis: Pathophysiology, clinical presentation and therapy". World J Hepatol. 7 (7): 926–41. doi:10.4254/wjh.v7.i7.926. PMC 4419097. PMID 25954476.
  3. Nguyen DL, Juran BD, Lazaridis KN (2010). "Primary biliary cirrhosis". Best Pract Res Clin Gastroenterol. 24 (5): 647–54. doi:10.1016/j.bpg.2010.07.006. PMC 2958170. PMID 20955967.


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