Primary amyloidosis MRI: Difference between revisions
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==Overview== | ==Overview== | ||
MRI is commonly done to assess for amyloid deposition in particular organs. It can also be done to rule out other causes of organ dysfunction. However, MRI is more sensitive than CT in the diagnosis of amyloidosis. A cardiac [[MRI]] is used when an [[echocardiogram]] fails to differentiate amyloidosis from [[hypertrophic cardiomyopathy]]. | [[Magnetic resonance imaging|MRI]] is commonly done to assess for [[amyloid]] deposition in particular organs. It can also be done to rule out other causes of organ dysfunction. However, [[Magnetic resonance imaging|MRI]] is more sensitive than [[CT-scans|CT]] in the diagnosis of amyloidosis. A cardiac [[MRI]] is used when an [[echocardiogram]] fails to differentiate amyloidosis from [[hypertrophic cardiomyopathy]]. | ||
==MRI== | ==MRI== | ||
In cardiac amyloidosis the MRI findings may include<ref name="pmid24847009">{{cite journal| author=Falk RH, Quarta CC, Dorbala S| title=How to image cardiac amyloidosis. | journal=Circ Cardiovasc Imaging | year= 2014 | volume= 7 | issue= 3 | pages= 552-62 | pmid=24847009 | doi=10.1161/CIRCIMAGING.113.001396 | pmc=4118308 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24847009 }} </ref>: | In cardiac amyloidosis the MRI findings may include<ref name="pmid24847009">{{cite journal| author=Falk RH, Quarta CC, Dorbala S| title=How to image cardiac amyloidosis. | journal=Circ Cardiovasc Imaging | year= 2014 | volume= 7 | issue= 3 | pages= 552-62 | pmid=24847009 | doi=10.1161/CIRCIMAGING.113.001396 | pmc=4118308 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24847009 }} </ref>: | ||
* | *[[Cardiomegaly]] with heterogeneous decreased attenuation | ||
* Cardiac calcifications | *[[Cardiac]] [[Calcification|calcifications]] | ||
* Pericardial effusion (rare) | *[[Pericardial effusion]] (rare) | ||
In hepatic amyloidosis the MRI scan findings may include: | In hepatic amyloidosis the [[Magnetic resonance imaging|MRI]] scan findings may include: | ||
* Liver enlargement with heterogeneous decreased attenuation | *[[Hepatomegaly|Liver enlargement]] with heterogeneous decreased attenuation | ||
* Asymmetric and triangular hepatomegaly with the apex at the falciform ligament (due to mild atrophic change of the lateral border of both hepatic lobes) | * Asymmetric and triangular [[hepatomegaly]] with the apex at the [[falciform ligament]] (due to mild atrophic change of the lateral border of both hepatic lobes) | ||
* Parenchyma calcification (rare) | * Parenchyma [[calcification]] (rare) | ||
In renal amyloidosis the MRI findings may include: | In renal amyloidosis the [[Magnetic resonance imaging|MRI]] findings may include: | ||
* Kidney enlargement with heterogeneous decreased attenuation | *[[Kidney]] enlargement with heterogeneous decreased attenuation | ||
* Parenchyma calcification (rare) | * Parenchyma [[calcification]] (rare) | ||
In amyloidosis involving the peripheral nerves the MRI findings may include: | In amyloidosis involving the peripheral nerves the [[MRI scan|MRI]] findings may include: | ||
*Perineural enhancement | *Perineural enhancement | ||
Revision as of 17:53, 30 October 2019
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Primary amyloidosis Microchapters |
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Primary amyloidosis MRI On the Web |
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American Roentgen Ray Society Images of Primary amyloidosis MRI |
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Risk calculators and risk factors for Primary amyloidosis MRI |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shyam Patel [2]
Overview
MRI is commonly done to assess for amyloid deposition in particular organs. It can also be done to rule out other causes of organ dysfunction. However, MRI is more sensitive than CT in the diagnosis of amyloidosis. A cardiac MRI is used when an echocardiogram fails to differentiate amyloidosis from hypertrophic cardiomyopathy.
MRI
In cardiac amyloidosis the MRI findings may include[1]:
- Cardiomegaly with heterogeneous decreased attenuation
- Cardiac calcifications
- Pericardial effusion (rare)
In hepatic amyloidosis the MRI scan findings may include:
- Liver enlargement with heterogeneous decreased attenuation
- Asymmetric and triangular hepatomegaly with the apex at the falciform ligament (due to mild atrophic change of the lateral border of both hepatic lobes)
- Parenchyma calcification (rare)
In renal amyloidosis the MRI findings may include:
- Kidney enlargement with heterogeneous decreased attenuation
- Parenchyma calcification (rare)
In amyloidosis involving the peripheral nerves the MRI findings may include:
- Perineural enhancement
Images
References
- ↑ Falk RH, Quarta CC, Dorbala S (2014). "How to image cardiac amyloidosis". Circ Cardiovasc Imaging. 7 (3): 552–62. doi:10.1161/CIRCIMAGING.113.001396. PMC 4118308. PMID 24847009.
- ↑ Case courtesy of Dr David Cuevas, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/61600">rID: 61600</a>
- ↑ Case courtesy of Dr Rebecca Dumont Walter, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/42915">rID: 42915</a>