Premature rupture of membranes resident survival guide: Difference between revisions

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Common risk factors in the development of PROM include :
Common risk factors in the development of PROM include :
*Maternal risk factors:
*Maternal risk factors:
**[[Chorioamnionitis]]
**[[Sepsis]]
**[[sepsis]]
**Previous history of PROM, recurrence risk is 16%–32% as compared with 4% in women with a prior uncomplicated term delivery)
**previous history of PROM
**Chronic steroid therapy
**Additional factors are similar to those for preterm birth such as
**Abnormal bleeding during the second trimester or late in the pregnancy,
***Abnormal bleeding during the second trimester or late in the pregnancy,
**Low body mass index (BMI < 19.8 kg/m2)
***Low BMI
**Smoking and drug abuse
***Reduced cervical length
**Low socioeconomic status
***Smoking and drug abuse
**Deficiency of copper or vitamin C, along with connective tissue disorders such as  Ehlers-Danlos syndrome, systemic lupus erythematosus are also linked to increased risk of PROM.
***Low socioeconomic status
**Direct abdominal trauma
***deficiency of copper or vitamin C, along with connective tissue disorders are also linked to increased risk of PROM.
**Preterm labor
**Anemia
 
*Uteroplacental Factors:
**Uterine anomalies (such as uterine septum)
**Placental abruption
**Advanced cervical dilatation (cervical insufficiency)
**Prior cervical conization
**Cervical shortening in the 2nd trimester (< 2.5 cm)
**Uterine overdistention (polyhydramnios, multiple pregnancy)
**Intra-amniotic infection (chorioamnionitis)
**Multiple bimanual vaginal examinations (but not sterile speculum or transvaginal ultrasound examinations)
 
*Fetal factors include :
*Fetal factors include :
**Multiple pregnancy (preterm PROM complicates 7%–10% of twin pregnancies)
**Prematurity
**Prematurity
**[[Infection]]
**[[Infection]]
**[[Cord prolapse]]
**[[Cord prolapse]]
**[[Malpresentation]]. <ref name="pmid7088456">{{cite journal| author=Naeye RL| title=Factors that predispose to premature rupture of the fetal membranes. | journal=Obstet Gynecol | year= 1982 | volume= 60 | issue= 1 | pages= 93-8 | pmid=7088456 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7088456  }} </ref>
**[[Malpresentation]]. <ref name="pmid7088456">{{cite journal| author=Naeye RL| title=Factors that predispose to premature rupture of the fetal membranes. | journal=Obstet Gynecol | year= 1982 | volume= 60 | issue= 1 | pages= 93-8 | pmid=7088456 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7088456  }} </ref>
===Common Causes===
* [[Common cause 1]]
* [[Common cause 2]]
* [[Common cause 3]]
* [[Common cause 4]]
* [[Common cause 5]]


==Diagnosis==
==Diagnosis==

Revision as of 06:00, 19 February 2021


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rinky Agnes Botleroo, M.B.B.S.

Synonyms and keywords:

Overview

This section provides a short and straight to the point overview of the disease or symptom. The first sentence of the overview must contain the name of the disease.

Causes

Common risk factors in the development of PROM include :

  • Maternal risk factors:
    • Sepsis
    • Previous history of PROM, recurrence risk is 16%–32% as compared with 4% in women with a prior uncomplicated term delivery)
    • Chronic steroid therapy
    • Abnormal bleeding during the second trimester or late in the pregnancy,
    • Low body mass index (BMI < 19.8 kg/m2)
    • Smoking and drug abuse
    • Low socioeconomic status
    • Deficiency of copper or vitamin C, along with connective tissue disorders such as Ehlers-Danlos syndrome, systemic lupus erythematosus are also linked to increased risk of PROM.
    • Direct abdominal trauma
    • Preterm labor
    • Anemia
  • Uteroplacental Factors:
    • Uterine anomalies (such as uterine septum)
    • Placental abruption
    • Advanced cervical dilatation (cervical insufficiency)
    • Prior cervical conization
    • Cervical shortening in the 2nd trimester (< 2.5 cm)
    • Uterine overdistention (polyhydramnios, multiple pregnancy)
    • Intra-amniotic infection (chorioamnionitis)
    • Multiple bimanual vaginal examinations (but not sterile speculum or transvaginal ultrasound examinations)

Diagnosis

Shown below is an algorithm summarizing the diagnosis of [[disease name]] according to the [...] guidelines.

 
 
 
History suggestive of PROM<be>(leakage of fluid from the vagina)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Physical examination findings confirm PROM
•Pooling of fluid
•Positive nitrazine and Ferning tests
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Sterile speculum examination assess dilation and ultrasound if indicated
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
PROM ruled-out
 
 
 
PROM confirmed
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Check gestational age
•Arrange transportation to tertiary care if possible
•Arrange prompt consult with obstetrician
Fetal non-stress test and ECG to assess well being
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Induce delivery with oxytocin if at-term gestation
 
Plan delivery if any signs of infection, placental insufficiency, fetal distress, or active labor
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
24-31 weeks
Antibiotics+steroids
•Delivery if lung maturity is satisfactory
 
32-33 weeks
Antibiotics+steroids
Delivery at 34 weeks or amniocentesis if abortion is suspected
 
34-36 weeks
Group B strep prophylaxis
Delivery

Treatment

Shown below is an algorithm summarizing the treatment of [[disease name]] according the the [...] guidelines.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Do's

  • The content in this section is in bullet points.

Don'ts

  • The content in this section is in bullet points.

References

  1. Naeye RL (1982). "Factors that predispose to premature rupture of the fetal membranes". Obstet Gynecol. 60 (1): 93–8. PMID 7088456.


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