Polymyxin B sulfate: Difference between revisions

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{{Polymyxin B sulfate}}
{{Polymyxin B sulfate}}
'''''For patient information, click <u>[[Neomycin, polymyxin, and bacitracin topical (patient information)|here]]</u> and <u>[[Neomycin, polymyxin, and bacitracin ophthalmic (patient information)|here]]</u>'''''.
{{CMG}}; {{AE}} {{MM}}
{{CMG}}; {{AE}} {{MM}}
==Overview==
==Overview==
'''Neosporin''' is an antibiotic product marketed for the prevention of [[infection]]s and speeding the healing of [[wound]]s.
'''Neosporin''' is an antibiotic product marketed for the prevention of [[infection]]s and speeding the healing of [[wound]]s.
The original ointment contains three different antibiotics: [[bacitracin]], [[neomycin]], and [[polymyxin B]], in a relatively low molecular weight patented base of cocoa butter, cottonseed oil, sodium pyruvate, tocopheryl acetate, and [[petroleum jelly]].
The original ointment contains three different antibiotics: [[bacitracin]], [[neomycin]], and [[polymyxin B]], in a relatively low molecular weight patented base of cocoa butter, cottonseed oil, sodium pyruvate, tocopheryl acetate, and [[petroleum jelly]].
The generic name for these products, regardless of the base, is "Triple Antibiotic Ointment".
In China, this product is called "Complex Polymyxin B Ointment," which is manufactured by Zhejiang Reachall Pharmaceutical. The product was also marketed by The [[Upjohn]] Company under the name "Mycitracin", until 1997 when that name was acquired by Johnson & Johnson.<ref>{{Cite news
|publication-date=1997 June 5
|title=McNeil Consumer Products Co. strengthens worldwide lead in OTC pain reliever market
|format=Press Release
| periodical=Business Wire
|publisher=Business Wire
| publication-place=Fort Washington, PA
|url=http://www.thefreelibrary.com/-a019478196
|accessdate=June 28, 2011
|postscript=<!-- Bot inserted parameter. Either remove it; or change its value to "." for the cite to end in a ".", as necessary. -->{{inconsistent citations}}
}}</ref>
<!-- alternate URL, if that one ever goes defunct: http://findarticles.com/p/articles/mi_m0EIN/is_1997_June_5/ai_19478196/ -->


==Category==
==Category==

Latest revision as of 17:54, 8 January 2014

Polymyxin B sulfate
NEOSPORIN® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Dosage and Administration
How Supplied
Labels and Packages

For patient information, click here and here.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]

Overview

Neosporin is an antibiotic product marketed for the prevention of infections and speeding the healing of wounds. The original ointment contains three different antibiotics: bacitracin, neomycin, and polymyxin B, in a relatively low molecular weight patented base of cocoa butter, cottonseed oil, sodium pyruvate, tocopheryl acetate, and petroleum jelly.

Category

Polymyxin antibiotic

US Brand Names

NEOSPORIN®

FDA Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Dosage and Administration | How Supplied

Mechanism of Action

Polymyxin antibiotic is a surface active agent which penetrates into and disrupts the bacterial cell membrane. It has been shown to have bactericidal activity against most strains of the microorganisms.[1]

References

  1. ↑ "NEOSPORIN (NEOMYCIN AND POLYMYXIN B SULFATES AND GRAMICIDIN) SOLUTION [MONARCH PHARMACEUTICALS, INC.]". Text " accessdate" ignored (help)
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