Polycythemia vera physical examination: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Polycythemia vera}} | {{Polycythemia vera}} | ||
{{CMG}}{{AE}}{{MJK}} {{shyam}} | {{CMG}} {{AE}} {{IO}} {{MJK}}; {{shyam}} | ||
==Overview== | ==Overview== | ||
Patients with polycythemia vera are usually well-appearing. Physical examination of patients with polycythemia vera is usually remarkable for | Patients with polycythemia vera are usually well-appearing. Physical examination of patients with polycythemia vera is usually remarkable for ruddy and plethoric face, [[fever]], and [[splenomegaly]]. | ||
==Physical Examination== | ==Physical Examination== | ||
Common physical examination findings associated with polycythemia vera include:<ref name="cancer.ca">Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia/leukemia/polycythemia-vera/?region=ab</ref><ref name="pmid22211080">{{cite journal| author=Dust N, Daboval T, Guerra L| title=Evaluation and management of priapism in a newborn: A case report and review of the literature. | journal=Paediatr Child Health | year= 2011 | volume= 16 | issue= 1 | pages= e6-8 | pmid=22211080 | doi= | pmc=PMC3043029 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22211080 }} </ref> | Common physical examination findings associated with polycythemia vera include:<ref name="cancer.ca">Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia/leukemia/polycythemia-vera/?region=ab</ref><ref name="pmid22211080">{{cite journal| author=Dust N, Daboval T, Guerra L| title=Evaluation and management of priapism in a newborn: A case report and review of the literature. | journal=Paediatr Child Health | year= 2011 | volume= 16 | issue= 1 | pages= e6-8 | pmid=22211080 | doi= | pmc=PMC3043029 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22211080 }} </ref><ref name="pmid26324368">{{cite journal |vauthors=Stein BL, Oh ST, Berenzon D, Hobbs GS, Kremyanskaya M, Rampal RK, Abboud CN, Adler K, Heaney ML, Jabbour EJ, Komrokji RS, Moliterno AR, Ritchie EK, Rice L, Mascarenhas J, Hoffman R |title=Polycythemia Vera: An Appraisal of the Biology and Management 10 Years After the Discovery of JAK2 V617F |journal=J. Clin. Oncol. |volume=33 |issue=33 |pages=3953–60 |date=November 2015 |pmid=26324368 |pmc=4979103 |doi=10.1200/JCO.2015.61.6474 |url=}}</ref> | ||
===Appearance of the Patient=== | ===Appearance of the Patient=== | ||
*Patients | *Patients with polycythemia vera usually have a ruddy, plethoric complexion. | ||
===Vital Signs=== | ===Vital Signs=== | ||
*[[Fever]] | *[[Fever]] | ||
*[[Systolic hypertension]] | |||
*Diastolic [[hypertension]] | |||
===Skin=== | ===Skin=== | ||
*[[Bruises]] | *[[Bruises]] | ||
*[[Petechiae]] | *[[Petechiae]] | ||
*[[Ulcers]] | *[[Ulcers]] | ||
*[[Plethora]] | *[[Plethora]] in face | ||
*[[Tophus|Gouty nodules]] | *[[Tophus|Gouty nodules]] | ||
*[[Post-phlebitis syndrome]] if deep vein thrombosis develops | *[[Post-phlebitis syndrome]] if [[deep vein thrombosis]] develops | ||
*[[Erythema]] in extremities | |||
===HEENT=== | ===HEENT=== | ||
*Decreased vision acuity | *Decreased vision acuity | ||
*Numbness | *[[Numbness]] or weakness from [[cerebrovascular event]] | ||
*[[Conjunctival]] [[plethora]] | |||
*Engorged [[retinal veins]] | |||
===Neck=== | ===Neck=== | ||
*[[Lymphadenopathy]] | *[[Lymphadenopathy]] | ||
===Lungs=== | ===Lungs=== | ||
*Vesicular breath sounds | *Vesicular breath sounds | ||
*[[Wheezing]] | *[[Wheezing]] | ||
===Heart=== | |||
* Cardiovascular examination of patients with polycythemia vera is usually normal. | |||
===Abdomen=== | ===Abdomen=== | ||
*[[Splenomegaly]] | *[[Splenomegaly]] | ||
===Back=== | |||
* Back examination of patients with polycythemia vera is usually normal. | |||
===Genitourinary=== | ===Genitourinary=== | ||
*[[lymphadenopathy|Inguinal lymphadenopathy]] | *[[lymphadenopathy|Inguinal lymphadenopathy]] | ||
*[[Priapism]] | *[[Priapism]] | ||
===Neuromuscular=== | |||
* Neuromuscular examination of patients with polycythemia vera is usually normal. | |||
===Extremities=== | |||
*[[Numbness]] | |||
==References== | ==References== | ||
Latest revision as of 03:07, 14 September 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ifeoma Odukwe, M.D. [2] Mohamad Alkateb, MBBCh [3]; Shyam Patel [4]
Overview
Patients with polycythemia vera are usually well-appearing. Physical examination of patients with polycythemia vera is usually remarkable for ruddy and plethoric face, fever, and splenomegaly.
Physical Examination
Common physical examination findings associated with polycythemia vera include:[1][2][3]
Appearance of the Patient
- Patients with polycythemia vera usually have a ruddy, plethoric complexion.
Vital Signs
- Fever
- Systolic hypertension
- Diastolic hypertension
Skin
- Bruises
- Petechiae
- Ulcers
- Plethora in face
- Gouty nodules
- Post-phlebitis syndrome if deep vein thrombosis develops
- Erythema in extremities
HEENT
- Decreased vision acuity
- Numbness or weakness from cerebrovascular event
- Conjunctival plethora
- Engorged retinal veins
Neck
Lungs
- Vesicular breath sounds
- Wheezing
Heart
- Cardiovascular examination of patients with polycythemia vera is usually normal.
Abdomen
Back
- Back examination of patients with polycythemia vera is usually normal.
Genitourinary
Neuromuscular
- Neuromuscular examination of patients with polycythemia vera is usually normal.
Extremities
References
- ↑ Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia/leukemia/polycythemia-vera/?region=ab
- ↑ Dust N, Daboval T, Guerra L (2011). "Evaluation and management of priapism in a newborn: A case report and review of the literature". Paediatr Child Health. 16 (1): e6–8. PMC 3043029. PMID 22211080.
- ↑ Stein BL, Oh ST, Berenzon D, Hobbs GS, Kremyanskaya M, Rampal RK, Abboud CN, Adler K, Heaney ML, Jabbour EJ, Komrokji RS, Moliterno AR, Ritchie EK, Rice L, Mascarenhas J, Hoffman R (November 2015). "Polycythemia Vera: An Appraisal of the Biology and Management 10 Years After the Discovery of JAK2 V617F". J. Clin. Oncol. 33 (33): 3953–60. doi:10.1200/JCO.2015.61.6474. PMC 4979103. PMID 26324368.