Polyarteritis nodosa causes

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Polyarteritis nodosa Microchapters


Patient Information


Historical Perspective




Differentiating Polyarteritis nodosa from other Diseases

Epidemiology and Demographics

Risk Factors


Natural History, Complications and Prognosis


Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings


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Echocardiography or Ultrasound

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Ali Poyan Mehr, M.D. [2] Associate Editor(s)-in-Chief: Sargun Singh Walia M.B.B.S.[3]


The common causes of PAN are idiopathic, Hepatitis B infection, Hepatitis C infection, hairy cell leukemia and drug induced. Less common causes include varicella-zoster virus, parvovirus B-19, cytomegalovirus, human T-cell leukemia virus etc.


Common Causes

PAN may be caused by:

Less Common Causes

PAN may be caused by:


  1. Stone JH (October 2002). "Polyarteritis nodosa". JAMA. 288 (13): 1632–9. PMID 12350194.
  2. Guillevin L, Mahr A, Callard P, Godmer P, Pagnoux C, Leray E; et al. (2005). "Hepatitis B virus-associated polyarteritis nodosa: clinical characteristics, outcome, and impact of treatment in 115 patients". Medicine (Baltimore). 84 (5): 313–22. PMID 16148731.
  3. Ramos-Casals M, Muñoz S, Medina F, Jara LJ, Rosas J, Calvo-Alen J; et al. (2009). "Systemic autoimmune diseases in patients with hepatitis C virus infection: characterization of 1020 cases (The HISPAMEC Registry)". J Rheumatol. 36 (7): 1442–8. doi:10.3899/jrheum.080874. PMID 19369460.
  4. Hasler P, Kistler H, Gerber H (1995). "Vasculitides in hairy cell leukemia". Semin Arthritis Rheum. 25 (2): 134–42. PMID 8578313.
  5. Imanishi H, Tsuruta D, Oshimo T, Sowa J, Mizuno N, Nakagawa K, Ishii M (August 2012). "Cutaneous polyarteritis nodosa induced by Mycobacterium tuberculosis". J. Dermatol. 39 (8): 738–9. doi:10.1111/j.1346-8138.2011.01398.x. PMID 22035185.
  6. Patel N, Patel N, Khan T, Patel N, Espinoza LR (December 2011). "HIV infection and clinical spectrum of associated vasculitides". Curr Rheumatol Rep. 13 (6): 506–12. doi:10.1007/s11926-011-0214-6. PMID 21989711.
  7. Watts RA, Mooney J, Lane SE, Scott DG (July 2004). "Rheumatoid vasculitis: becoming extinct?". Rheumatology (Oxford). 43 (7): 920–3. doi:10.1093/rheumatology/keh210. PMID 15126674.
  8. Nakano H, Ooka S, Shibata T, Ogawa H, Ito H, Takakuwa Y, Tonooka K, Maeda A, Yamasaki Y, Kiyokawa T, Nagafuchi H, Yamada H, Ozaki S (September 2012). "Cutaneous polyarteritis nodosa associated with HLA-B39-positive undifferentiated spondyloarthritis in a Japanese patient". Mod Rheumatol. 22 (5): 783–6. doi:10.1007/s10165-011-0576-7. PMID 22270344.
  9. Pagnini I, Simonini G, Lippi F, Azzari C, Cimaz R (2012). "Cutaneous polyarteritis nodosa and common variable immunodeficiency: a previously unreported association". Clin. Exp. Rheumatol. 30 (1 Suppl 70): S169. PMID 22260879.
  10. Oulego-Erroz I, Gautreaux-Minaya S, Martinez-Sáenz de Jubera J, Naranjo-Vivas D, Fernéndez-Hernández S, Muñíz-Fontán M (September 2011). "Coexistence of polyarteritis nodosa and psoriatic arthritis in a child: an unreported association: Polyarteritis nodosa and Psoriatic arthitritis". Eur. J. Pediatr. 170 (9): 1213–5. doi:10.1007/s00431-011-1459-9. PMID 21487680.

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