Poly ICLC

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Poly ICLC
Clinical data
ATC code
Identifiers
E number{{#property:P628}}
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Poly ICLC is an immunostimulant.

It consists of carboxymethylcellulose, polyinosinic-polycytidylic acid, and poly-L-lysine double-stranded RNA.[1]

It is a ligand for toll like receptor-3.[2]

References

  1. "Definition of poly ICLC - National Cancer Institute Drug Dictionary". Retrieved 2007-11-13.
  2. Zhu X, Nishimura F, Sasaki K; et al. (2007). "Toll like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models". Journal of translational medicine. 5: 10. doi:10.1186/1479-5876-5-10. PMID 17295916.

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http://www.cancer.gov/Templates/drugdictionary.aspx?CdrID=39559