Plexin A1: Difference between revisions
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'''Plexin-A1''' is a [[protein]] that in humans is encoded by the ''PLXNA1'' [[gene]].<ref name="pmid8570614">{{cite journal |vauthors=Maestrini E, Tamagnone L, Longati P, Cremona O, Gulisano M, Bione S, Tamanini F, Neel BG, Toniolo D, Comoglio PM | title = A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor | journal = Proc Natl Acad Sci U S A | volume = 93 | issue = 2 | pages = 674–8 |date=Mar 1996 | pmid = 8570614 | pmc = 40111 | doi = 10.1073/pnas.93.2.674}}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PLXNA1 plexin A1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5361| accessdate = }}</ref> | '''Plexin-A1''' is a [[protein]] that in humans is encoded by the ''PLXNA1'' [[gene]].<ref name="pmid8570614">{{cite journal |vauthors=Maestrini E, Tamagnone L, Longati P, Cremona O, Gulisano M, Bione S, Tamanini F, Neel BG, Toniolo D, Comoglio PM | title = A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor | journal = Proc Natl Acad Sci U S A | volume = 93 | issue = 2 | pages = 674–8 |date=Mar 1996 | pmid = 8570614 | pmc = 40111 | doi = 10.1073/pnas.93.2.674| bibcode =1996PNAS...93..674M }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PLXNA1 plexin A1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5361| accessdate = }}</ref> | ||
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*{{cite journal |vauthors=Zanata SM, Hovatta I, Rohm B, Püschel AW |title=Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in Semaphorin 3A-induced cytoskeletal collapse. |journal=J. Neurosci. |volume=22 |issue= 2 |pages= 471–7 |year= 2002 |pmid= 11784792 |doi= }} | *{{cite journal |vauthors=Zanata SM, Hovatta I, Rohm B, Püschel AW |title=Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in Semaphorin 3A-induced cytoskeletal collapse. |journal=J. Neurosci. |volume=22 |issue= 2 |pages= 471–7 |year= 2002 |pmid= 11784792 |doi= }} | ||
*{{cite journal |vauthors=Mitsui N, Inatome R, Takahashi S, etal |title=Involvement of Fes/Fps tyrosine kinase in semaphorin3A signaling. |journal=EMBO J. |volume=21 |issue= 13 |pages= 3274–85 |year= 2002 |pmid= 12093729 | pmc=125392 |doi= 10.1093/emboj/cdf328 }} | *{{cite journal |vauthors=Mitsui N, Inatome R, Takahashi S, etal |title=Involvement of Fes/Fps tyrosine kinase in semaphorin3A signaling. |journal=EMBO J. |volume=21 |issue= 13 |pages= 3274–85 |year= 2002 |pmid= 12093729 | pmc=125392 |doi= 10.1093/emboj/cdf328 }} | ||
*{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 | pmc=139241 |doi= 10.1073/pnas.242603899 }} | *{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 | pmc=139241 |doi= 10.1073/pnas.242603899 |bibcode=2002PNAS...9916899M }} | ||
*{{cite journal |vauthors=Usui H, Taniguchi M, Yokomizo T, Shimizu T |title=Plexin-A1 and plexin-B1 specifically interact at their cytoplasmic domains. |journal=Biochem. Biophys. Res. Commun. |volume=300 |issue= 4 |pages= 927–31 |year= 2003 |pmid= 12559962 |doi= 10.1016/S0006-291X(02)02966-2}} | *{{cite journal |vauthors=Usui H, Taniguchi M, Yokomizo T, Shimizu T |title=Plexin-A1 and plexin-B1 specifically interact at their cytoplasmic domains. |journal=Biochem. Biophys. Res. Commun. |volume=300 |issue= 4 |pages= 927–31 |year= 2003 |pmid= 12559962 |doi= 10.1016/S0006-291X(02)02966-2}} | ||
*{{cite journal |vauthors=Bachelder RE, Lipscomb EA, Lin X, etal |title=Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells. |journal=Cancer Res. |volume=63 |issue= 17 |pages= 5230–3 |year= 2003 |pmid= 14500350 |doi= }} | *{{cite journal |vauthors=Bachelder RE, Lipscomb EA, Lin X, etal |title=Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells. |journal=Cancer Res. |volume=63 |issue= 17 |pages= 5230–3 |year= 2003 |pmid= 14500350 |doi= }} | ||
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*{{cite journal |vauthors=Toyofuku T, Zhang H, Kumanogoh A, etal |title=Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2. |journal=Genes Dev. |volume=18 |issue= 4 |pages= 435–47 |year= 2004 |pmid= 14977921 | pmc=359397 |doi= 10.1101/gad.1167304 }} | *{{cite journal |vauthors=Toyofuku T, Zhang H, Kumanogoh A, etal |title=Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2. |journal=Genes Dev. |volume=18 |issue= 4 |pages= 435–47 |year= 2004 |pmid= 14977921 | pmc=359397 |doi= 10.1101/gad.1167304 }} | ||
*{{cite journal |vauthors=Turner LJ, Nicholls S, Hall A |title=The activity of the plexin-A1 receptor is regulated by Rac. |journal=J. Biol. Chem. |volume=279 |issue= 32 |pages= 33199–205 |year= 2004 |pmid= 15187088 |doi= 10.1074/jbc.M402943200 }} | *{{cite journal |vauthors=Turner LJ, Nicholls S, Hall A |title=The activity of the plexin-A1 receptor is regulated by Rac. |journal=J. Biol. Chem. |volume=279 |issue= 32 |pages= 33199–205 |year= 2004 |pmid= 15187088 |doi= 10.1074/jbc.M402943200 }} | ||
*{{cite journal |vauthors=Muzny DM, Scherer SE, Kaul R, etal |title=The DNA sequence, annotation and analysis of human chromosome 3. |journal=Nature |volume=440 |issue= 7088 |pages= 1194–8 |year= 2006 |pmid= 16641997 |doi= 10.1038/nature04728 }} | *{{cite journal |vauthors=Muzny DM, Scherer SE, Kaul R, etal |title=The DNA sequence, annotation and analysis of human chromosome 3. |journal=Nature |volume=440 |issue= 7088 |pages= 1194–8 |year= 2006 |pmid= 16641997 |doi= 10.1038/nature04728 |bibcode=2006Natur.440.1194M }} | ||
}} | }} | ||
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Latest revision as of 23:11, 25 June 2018
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Plexin-A1 is a protein that in humans is encoded by the PLXNA1 gene.[1][2]
Interactions
Plexin A1 has been shown to interact with AKT1.[3]
References
- ↑ Maestrini E, Tamagnone L, Longati P, Cremona O, Gulisano M, Bione S, Tamanini F, Neel BG, Toniolo D, Comoglio PM (Mar 1996). "A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor". Proc Natl Acad Sci U S A. 93 (2): 674–8. Bibcode:1996PNAS...93..674M. doi:10.1073/pnas.93.2.674. PMC 40111. PMID 8570614.
- ↑ "Entrez Gene: PLXNA1 plexin A1".
- ↑ Turner, Laura J; Nicholls Sarah; Hall Alan (Aug 2004). "The activity of the plexin-A1 receptor is regulated by Rac". J. Biol. Chem. United States. 279 (32): 33199–205. doi:10.1074/jbc.M402943200. ISSN 0021-9258. PMID 15187088.
Further reading
- Takahashi T, Fournier A, Nakamura F, et al. (1999). "Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors". Cell. 99 (1): 59–69. doi:10.1016/S0092-8674(00)80062-8. PMID 10520994.
- Tamagnone L, Artigiani S, Chen H, et al. (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates". Cell. 99 (1): 71–80. doi:10.1016/S0092-8674(00)80063-X. PMID 10520995.
- Rohm B, Rahim B, Kleiber B, et al. (2001). "The semaphorin 3A receptor may directly regulate the activity of small GTPases". FEBS Lett. 486 (1): 68–72. doi:10.1016/S0014-5793(00)02240-7. PMID 11108845.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
- Takahashi T, Strittmatter SM (2001). "Plexina1 autoinhibition by the plexin sema domain". Neuron. 29 (2): 429–39. doi:10.1016/S0896-6273(01)00216-1. PMID 11239433.
- Zanata SM, Hovatta I, Rohm B, Püschel AW (2002). "Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in Semaphorin 3A-induced cytoskeletal collapse". J. Neurosci. 22 (2): 471–7. PMID 11784792.
- Mitsui N, Inatome R, Takahashi S, et al. (2002). "Involvement of Fes/Fps tyrosine kinase in semaphorin3A signaling". EMBO J. 21 (13): 3274–85. doi:10.1093/emboj/cdf328. PMC 125392. PMID 12093729.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Usui H, Taniguchi M, Yokomizo T, Shimizu T (2003). "Plexin-A1 and plexin-B1 specifically interact at their cytoplasmic domains". Biochem. Biophys. Res. Commun. 300 (4): 927–31. doi:10.1016/S0006-291X(02)02966-2. PMID 12559962.
- Bachelder RE, Lipscomb EA, Lin X, et al. (2003). "Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells". Cancer Res. 63 (17): 5230–3. PMID 14500350.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Toyofuku T, Zhang H, Kumanogoh A, et al. (2004). "Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2". Genes Dev. 18 (4): 435–47. doi:10.1101/gad.1167304. PMC 359397. PMID 14977921.
- Turner LJ, Nicholls S, Hall A (2004). "The activity of the plexin-A1 receptor is regulated by Rac". J. Biol. Chem. 279 (32): 33199–205. doi:10.1074/jbc.M402943200. PMID 15187088.
- Muzny DM, Scherer SE, Kaul R, et al. (2006). "The DNA sequence, annotation and analysis of human chromosome 3". Nature. 440 (7088): 1194–8. Bibcode:2006Natur.440.1194M. doi:10.1038/nature04728. PMID 16641997.
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