Pituitary adenoma staging

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]

Overview

According to American Joint Committee on Cancer classification and staging system for pituitary tumors there is no staging system available for pituitary adenoma. However radioanatomical classification places pituitary adenoma in 4 stages based on the size and degree of invasion.

Staging

The radioanatomical classification places adenomas into 1 of 4 stages:

  • Stage I involve microadenomas (<1 cm) without sellar expansion.
  • Stage II involve macroadenomas (≥1 cm) and may extend above the sella.
  • Stage III involve macroadenomas with enlargement and invasion of the floor or suprasellar extension.
  • Stage IV involve macroadenomas that cause destruction of the sella.

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