Peutz-Jeghers syndrome medical therapy: Difference between revisions

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There is no medical treatment for Peutz-Jeghers syndrome. Depending on the associated cancer, [[radiotherapy]] or [[chemotherapy]] may be considered.
There is no medical treatment for Peutz-Jeghers syndrome. Depending on the associated cancer, [[radiotherapy]] or [[chemotherapy]] may be considered.


Patients with Peutz-Jeghers syndrome are treated with intra-operative enteroscopy (IOE) and  double balloon enteroscopy (DBE).<ref name="KopacovaTacheci2009">{{cite journal|last1=Kopacova|first1=Marcela|last2=Tacheci|first2=Ilja|last3=Rejchrt|first3=Stanislav|last4=Bures|first4=Jan|title=Peutz-Jeghers syndrome: Diagnostic and therapeuticapproach|journal=World Journal of Gastroenterology|volume=15|issue=43|year=2009|pages=5397|issn=1007-9327|doi=10.3748/wjg.15.5397}}</ref>
Patients with Peutz-Jeghers syndrome are treated with intra-operative [[enteroscopy]] (IOE) and  double balloon [[enteroscopy]] (DBE).<ref name="KopacovaTacheci2009">{{cite journal|last1=Kopacova|first1=Marcela|last2=Tacheci|first2=Ilja|last3=Rejchrt|first3=Stanislav|last4=Bures|first4=Jan|title=Peutz-Jeghers syndrome: Diagnostic and therapeuticapproach|journal=World Journal of Gastroenterology|volume=15|issue=43|year=2009|pages=5397|issn=1007-9327|doi=10.3748/wjg.15.5397}}</ref>
*IOE
*'''Intra-operative [[enteroscopy]]'''
**Laparotomy (laparoscopy) with endoscopy
**[[Laparotomy]] ([[Laparoscopic surgery|laparoscopy]]) with [[endoscopy]] is done.
**Best modality for diagnostic and therapeutic procedure of the small bowel
**Best modality for diagnostic and therapeutic procedure of the small bowel.
*DBE
*'''Double balloon [[enteroscopy]]'''
**Allows examination and treatment of the Jejenum and Ileum
**Allows examination and treatment of the Jejenum and Ileum.


* Chemoprevention
* '''[[Chemoprophylaxis]]'''
**Proven efficacy of rapamycin for Peutz-Jeghers syndrome in a mouse model
**Proven efficacy of [[rapamycin]] for Peutz-Jeghers syndrome in a mouse model.


== References ==
== References ==

Revision as of 21:13, 20 December 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]

Overview

There is no medical treatment for Peutz-Jeghers syndrome. Depending on the associated cancer, radiotherapy or chemotherapy may be considered.

Medical Therapy

There is no medical treatment for Peutz-Jeghers syndrome. Depending on the associated cancer, radiotherapy or chemotherapy may be considered.

Patients with Peutz-Jeghers syndrome are treated with intra-operative enteroscopy (IOE) and double balloon enteroscopy (DBE).[1]

References

  1. Kopacova, Marcela; Tacheci, Ilja; Rejchrt, Stanislav; Bures, Jan (2009). "Peutz-Jeghers syndrome: Diagnostic and therapeuticapproach". World Journal of Gastroenterology. 15 (43): 5397. doi:10.3748/wjg.15.5397. ISSN 1007-9327.

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