Peutz-Jeghers syndrome medical therapy: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
Line 17: Line 17:


* Chemoprevention
* Chemoprevention
**Proven efficacy of rapamycin for Peutz-Jeghers syndrome in a mouse model [[File:Enteroscopy.jpg|none|thumb|300x300px|By Veharan (Own work) [CC BY-SA 4.0 (<nowiki>https://creativecommons.org/licenses/by-sa/4.0</nowiki>)], via Wikimedia Commons]]<ref>{{Cite web|url=https://upload.wikimedia.org/wikipedia/commons/5/5f/Enteroscopy.jpg|title=By Veharan (Own work) [CC BY-SA 4.0 (https://creativecommons.org/licenses/by-sa/4.0)], via Wikimedia Commons|last=|first=|date=|website=|publisher=|access-date=}}</ref>
**Proven efficacy of rapamycin for Peutz-Jeghers syndrome in a mouse model


== References ==
== References ==
{{reflist|2}}
{{reflist|2}}

Revision as of 13:53, 19 December 2017

Peutz-Jeghers syndrome Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Peutz-Jeghers syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural history, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Peutz-Jeghers syndrome medical therapy On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Peutz-Jeghers syndrome medical therapy

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Peutz-Jeghers syndrome medical therapy

CDC on Peutz-Jeghers syndrome medical therapy

Peutz-Jeghers syndrome medical therapy in the news

Blogs on Peutz-Jeghers syndrome medical therapy

Directions to Hospitals Treating Peutz-Jeghers syndrome

Risk calculators and risk factors for Peutz-Jeghers syndrome medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]

Overview

There is no medical treatment for Peutz-Jeghers syndrome. Depending on the associated cancer, radiotherapy or chemotherapy may be considered.

Medical Therapy

There is no medical treatment for Peutz-Jeghers syndrome. Depending on the associated cancer, radiotherapy or chemotherapy may be considered.

Patients with Peutz-Jeghers syndrome are treated with intra-operative enteroscopy (IOE) and double balloon enteroscopy (DBE).[1]

  • IOE
    • Laparotomy (laparoscopy) with endoscopy
    • Best modality for diagnostic and therapeutic procedure of the small bowel
  • DBE
    • Allows examination and treatment of the Jejenum and Ileum
  • Chemoprevention
    • Proven efficacy of rapamycin for Peutz-Jeghers syndrome in a mouse model

References

  1. Kopacova, Marcela; Tacheci, Ilja; Rejchrt, Stanislav; Bures, Jan (2009). "Peutz-Jeghers syndrome: Diagnostic and therapeuticapproach". World Journal of Gastroenterology. 15 (43): 5397. doi:10.3748/wjg.15.5397. ISSN 1007-9327.