Pentazocine
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2]
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Overview
Pentazocine is an analgesic opioid that is FDA approved for the {{{indicationType}}} of anesthesia; adjunct, labor pain, pain (moderate to severe). Common adverse reactions include gastrointestinal: nausea, vomiting, neurologic: dizziness, lightheadedness, psychiatric: euphoria.
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
Anesthesia; Adjunct: 30 mg IV, IM or SC every 3 to 4 hr as needed, MAX 360 mg/day; doses above 30 mg IV or 60 mg IM, SC are not recommended [1] Labor pain: a single 30 mg/dose IM (most common); OR 20 mg/dose IV for 2-3 doses at 2-3-hr intervals, as needed, after contractions have become regular [1] Pain (Moderate to Severe): 30 mg IV, IM or SC every 3-4 hr as needed, MAX 360 mg/day; doses above 30 mg IV or 60 mg IM, SC are not recommended [1]
Off-Label Use and Dosage (Adult)
Guideline-Supported Use
There is limited information about Off-Label Guideline-Supported Use of Pentazocine in adult patients.
Non–Guideline-Supported Use
There is limited information about Off-Label Non–Guideline-Supported Use of Pentazocine in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
Safety and effectiveness in children less than 12 yr of age not established Anesthesia; Adjunct: single 0.5 mg/kg IM dose [1]
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
There is limited information about Off-Label Guideline-Supported Use of Pentazocine in pediatric patients.
Non–Guideline-Supported Use
There is limited information about Off-Label Non–Guideline-Supported Use of Pentazocine in pediatric patients.
Contraindications
There is limited information regarding Pentazocine Contraindications in the drug label.
Warnings
There is limited information regarding Pentazocine Warnings' in the drug label.
Adverse Reactions
Clinical Trials Experience
There is limited information regarding Pentazocine Clinical Trials Experience in the drug label.
Postmarketing Experience
There is limited information regarding Pentazocine Postmarketing Experience in the drug label.
Drug Interactions
There is limited information regarding Pentazocine Drug Interactions in the drug label.
Use in Specific Populations
Pregnancy
Pregnancy Category (FDA):
There is no FDA guidance on usage of Pentazocine in women who are pregnant.
Pregnancy Category (AUS):
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Pentazocine in women who are pregnant.
Labor and Delivery
There is no FDA guidance on use of Pentazocine during labor and delivery.
Nursing Mothers
There is no FDA guidance on the use of Pentazocine in women who are nursing.
Pediatric Use
There is no FDA guidance on the use of Pentazocine in pediatric settings.
Geriatic Use
There is no FDA guidance on the use of Pentazocine in geriatric settings.
Gender
There is no FDA guidance on the use of Pentazocine with respect to specific gender populations.
Race
There is no FDA guidance on the use of Pentazocine with respect to specific racial populations.
Renal Impairment
There is no FDA guidance on the use of Pentazocine in patients with renal impairment.
Hepatic Impairment
There is no FDA guidance on the use of Pentazocine in patients with hepatic impairment.
Females of Reproductive Potential and Males
There is no FDA guidance on the use of Pentazocine in women of reproductive potentials and males.
Immunocompromised Patients
There is no FDA guidance one the use of Pentazocine in patients who are immunocompromised.
Administration and Monitoring
Administration
There is limited information regarding Pentazocine Administration in the drug label.
Monitoring
There is limited information regarding Pentazocine Monitoring in the drug label.
IV Compatibility
There is limited information regarding the compatibility of Pentazocine and IV administrations.
Overdosage
There is limited information regarding Pentazocine overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.
Pharmacology
There is limited information regarding Pentazocine Pharmacology in the drug label.
Mechanism of Action
There is limited information regarding Pentazocine Mechanism of Action in the drug label.
Structure
There is limited information regarding Pentazocine Structure in the drug label.
Pharmacodynamics
There is limited information regarding Pentazocine Pharmacodynamics in the drug label.
Pharmacokinetics
There is limited information regarding Pentazocine Pharmacokinetics in the drug label.
Nonclinical Toxicology
There is limited information regarding Pentazocine Nonclinical Toxicology in the drug label.
Clinical Studies
There is limited information regarding Pentazocine Clinical Studies in the drug label.
How Supplied
There is limited information regarding Pentazocine How Supplied in the drug label.
Storage
There is limited information regarding Pentazocine Storage in the drug label.
Images
Drug Images
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Package and Label Display Panel
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Patient Counseling Information
There is limited information regarding Pentazocine Patient Counseling Information in the drug label.
Precautions with Alcohol
Alcohol-Pentazocine interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
Brand Names
There is limited information regarding Pentazocine Brand Names in the drug label.
Look-Alike Drug Names
There is limited information regarding Pentazocine Look-Alike Drug Names in the drug label.
Drug Shortage Status
Price
References
The contents of this FDA label are provided by the National Library of Medicine.