Paroxysmal AV Block Epidemiology

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  • Given the difficulty in diagnosis, sporadic presentation and sparse literature available, the exact incidence and prevalence of paroxysmal AV block is unknown.
  • An unpublished study done at Beth Israel Deaconess Medical Centre in collaboration with a cardiology department in the Netherlands found that paroxysmal AV block was most associated with RBBBs followed by LBBBs, intraventricular conduction delays and normal QRS complexes.
    • An age presentation of 26-99 years of age, an equal incidence in both men and women and an increased prevalence in older individuals were also seen.
    • However, the association between paroxysmal AV block and RBBB is a matter of much debate, as it is not sure whether RBBB causes a direct effect or is a sign seen in an aging population. [1]
  • The ISSUE 2 study was characterised by a population of individuals with a high mean age, a history of recurrent syncope beginning in middle or older ages, and frequent injuries probably due to presentation without warning.[2]
  1. Lee S, Wellens HJ, Josephson ME (2009). "Paroxysmal atrioventricular block". Heart Rhythm. 6 (8): 1229–34. doi:10.1016/j.hrthm.2009.04.001. PMID 19632639.
  2. Brignole M, Sutton R, Menozzi C, Garcia-Civera R, Moya A, Wieling W; et al. (2006). "Early application of an implantable loop recorder allows effective specific therapy in patients with recurrent suspected neurally mediated syncope". Eur Heart J. 27 (9): 1085–92. doi:10.1093/eurheartj/ehi842. PMID 16569653.