Paroxysmal AV Block Epidemiology: Difference between revisions

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==Overview==
==Overview==
Exact data reflecting the epidemiology of paroxysmal AV block is unavailable. However certain studies have shown an increased incidence in the elderly, no genetic predisposition and an association with bundle branch blocks.  
Exact data reflecting the [[epidemiology]] of [[paroxysmal AV block]] is unavailable. However certain studies have shown an increased [[incidence]] in the elderly, no [[gender]] predisposition and an association with [[bundle branch blocks]].  


==Epidemiology==
==Epidemiology==
*Given the difficulty in diagnosis, sporadic presentation and sparse literature available, the exact incidence and prevalence of paroxysmal AV block is unknown.
*Given the difficulty in [[diagnosis]], [[sporadic]] presentation and sparse literature available, the exact [[incidence]] and [[prevalence]] of [[paroxysmal AV block]] is unknown.


*'''An unpublished study done at Beth Israel Deaconess Medical Centre in collaboration with a cardiology department in the Netherlands''' found that paroxysmal AV block was most associated with '''RBBBs followed by LBBBs, intraventricular conduction delays and normal QRS complexes'''.  
*'''An unpublished study done at Beth Israel Deaconess Medical Centre in collaboration with a [[cardiology]] department in the Netherlands''' found that [[paroxysmal AV bloc]]<nowiki/>k was most associated with '''[[RBBB]]<nowiki/>s followed by [[LBBB]]<nowiki/>s, [[intraventricular conduction delays]] and normal [[QRS complexes]]'''.  
**An age presentation of '''26-99 years of age, an equal incidence in both men and women and an increased prevalence in older individuals were also seen'''.
**An age presentation of '''26-99 years of age, an equal [[incidence]] in both men and women and an increased [[prevalence]] in older individuals were also seen'''.
**However, the association between paroxysmal AV block and RBBB is a matter of much debate, as it is not sure whether RBBB causes a direct effect or is a sign seen in an aging population. <ref name="pmid19632639">{{cite journal| author=Lee S, Wellens HJ, Josephson ME| title=Paroxysmal atrioventricular block. | journal=Heart Rhythm | year= 2009 | volume= 6 | issue= 8 | pages= 1229-34 | pmid=19632639 | doi=10.1016/j.hrthm.2009.04.001 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19632639  }} </ref>
**However, the association between [[paroxysmal AV block]] and [[RBBB]] is a matter of much debate, as it is not sure whether RBBB causes a direct effect or is a sign seen in an aging population.<ref name="pmid19632639">{{cite journal| author=Lee S, Wellens HJ, Josephson ME| title=Paroxysmal atrioventricular block. | journal=Heart Rhythm | year= 2009 | volume= 6 | issue= 8 | pages= 1229-34 | pmid=19632639 | doi=10.1016/j.hrthm.2009.04.001 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19632639  }} </ref>


*'''The ISSUE 2 study''' was characterised by a population of individuals with a '''high mean age, a history of recurrent syncope beginning in middle or older ages, and frequent injuries''' probably due to presentation without warning.<ref name="pmid16569653">{{cite journal| author=Brignole M, Sutton R, Menozzi C, Garcia-Civera R, Moya A, Wieling W | display-authors=etal| title=Early application of an implantable loop recorder allows effective specific therapy in patients with recurrent suspected neurally mediated syncope. | journal=Eur Heart J | year= 2006 | volume= 27 | issue= 9 | pages= 1085-92 | pmid=16569653 | doi=10.1093/eurheartj/ehi842 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16569653  }} </ref>
*'''The ISSUE 2 study''' was characterised by a population of individuals with a '''high [[mean]] age, a history of recurrent [[syncope]] beginning in middle or older ages, and frequent injuries''' probably due to presentation without warning.<ref name="pmid16569653">{{cite journal| author=Brignole M, Sutton R, Menozzi C, Garcia-Civera R, Moya A, Wieling W | display-authors=etal| title=Early application of an implantable loop recorder allows effective specific therapy in patients with recurrent suspected neurally mediated syncope. | journal=Eur Heart J | year= 2006 | volume= 27 | issue= 9 | pages= 1085-92 | pmid=16569653 | doi=10.1093/eurheartj/ehi842 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16569653  }} </ref>


==References==
==References==

Latest revision as of 08:49, 26 June 2020

Overview

Exact data reflecting the epidemiology of paroxysmal AV block is unavailable. However certain studies have shown an increased incidence in the elderly, no gender predisposition and an association with bundle branch blocks.

Epidemiology

  • The ISSUE 2 study was characterised by a population of individuals with a high mean age, a history of recurrent syncope beginning in middle or older ages, and frequent injuries probably due to presentation without warning.[2]

References

  1. Lee S, Wellens HJ, Josephson ME (2009). "Paroxysmal atrioventricular block". Heart Rhythm. 6 (8): 1229–34. doi:10.1016/j.hrthm.2009.04.001. PMID 19632639.
  2. Brignole M, Sutton R, Menozzi C, Garcia-Civera R, Moya A, Wieling W; et al. (2006). "Early application of an implantable loop recorder allows effective specific therapy in patients with recurrent suspected neurally mediated syncope". Eur Heart J. 27 (9): 1085–92. doi:10.1093/eurheartj/ehi842. PMID 16569653.