Parkinson's disease surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Surgery
Surgery and deep brain stimulation
Treating Parkinson's disease with surgery was once a common practice, but after the discovery of levodopa, surgery was restricted to only a few cases. Studies in the past few decades have led to great improvements in surgical techniques, and surgery is again being used in people with advanced PD for whom drug therapy is no longer sufficient.
Deep brain stimulation is presently the most used surgical means of treatment, but other surgical therapies that have shown promise include surgical lesion of the subthalamic nucleus[1] and of the internal segment of the globus pallidus, a procedure known as pallidotomy.[2]
References
- ↑ Guridi J, Obeso JA (2001). "The subthalamic nucleus, hemiballismus and Parkinson's disease: reappraisal of a neurosurgical dogma". Brain. 124 (Pt 1): 5–19. PMID 11133783.
- ↑ Fukuda M, Kameyama S, Yoshino M, Tanaka R, Narabayashi H (2000). "Neuropsychological outcome following pallidotomy and thalamotomy for Parkinson's disease". Stereotactic and functional neurosurgery. 74 (1): 11–20. PMID 11124660.