Papaveretum: Difference between revisions

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Papaveretum
Combination of
Morphine	Opioid analgesic
Papaverine	Antispasmodic
Codeine	Opioid analgesic
[[{{{component4}}}]]	? Class
[[{{{component5}}}]]	? Class
Clinical data
Trade names	Omnopon
ATC code	N02AA10 (WHO) ;
Identifiers
PubChem CID	24840907;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).

VisualWikitext

Latest revision as of 16:30, 11 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Papaveretum (BAN) is a preparation containing a mixture of hydrochloride salts of opium alkaloids. Since 1993, papaveretum has been defined in the British Pharmacopoeia (BP) as a mixture of 253 parts morphine hydrochloride, 23 parts papaverine hydrochloride, and 20 parts codeine hydrochloride.^[1] It is commonly marketed to medical agencies under the trade name Omnopon.

Although the use of papaveretum is now relatively uncommon following the wide availability of single-component opiates and synthetic opioids (e.g. pethidine) it is still used to relieve moderate to severe pain and for pre-operative sedation. In clinical settings, papaveretum is usually administered to patients via subcutaneous, intramuscular or intravenous routes. Additionally, the morphine syrettes found in combat medical kits issued to military personnel actually contain omnopon.

Prior to 1993, papaveretum also contained noscapine, though this component was removed from the BP formulation due to the genotoxic potential of noscapine.

References

↑ Edited by Sean C. Sweetman, ed. (November 30, 2004). Martindale: The complete drug reference (34th edition ed.). London: Pharmaceutical Press. ISBN 0-85369-550-4.

[1] Edited by Sean C. Sweetman, ed. (November 30, 2004). Martindale: The complete drug reference (34th edition ed.). London: Pharmaceutical Press. ISBN 0-85369-550-4.

[1]

@@ Line 1: / Line 1: @@
-{{CMG}}
+{{Drugbox
+| type              = combo
+| component1        = Morphine
+| class1            = [[Opioid analgesic]]
+| component2        = Papaverine
+| class2            = [[Antispasmodic]]
+| component3        = Codeine
+| class3            = Opioid analgesic
+<!-- Clinical data -->
+| tradename         = Omnopon
+| Drugs.com         =
+| MedlinePlus       =
+| pregnancy_AU      = <!-- A / B1 / B2 / B3 / C / D / X -->
+| pregnancy_US      = <!-- A / B            / C / D / X -->
+| pregnancy_category=
+| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
+| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
+| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
+| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
+| legal_status      =
+| routes_of_administration =
+<!-- Identifiers -->
+| CAS_number        =
+| ATCvet            =
+| ATC_prefix        = N02
+| ATC_suffix        = AA10
+| PubChem           = 24840907
+| DrugBank          =
+}}
+              __NOTOC__
+{{SI}}
+{{CMG}}
 ==Overview==
+'''Papaveretum''' ([[British Approved Name|BAN]]) is a preparation containing a mixture of [[hydrochloride]] salts of [[opium]] [[alkaloid]]s. Since 1993, papaveretum has been defined in the [[British Pharmacopoeia]] (BP) as a mixture of 253 parts [[morphine|morphine hydrochloride]], 23 parts [[papaverine|papaverine hydrochloride]], and 20 parts [[codeine|codeine hydrochloride]].<ref>{{cite book | editor= Edited by Sean C. Sweetman | title=[[Martindale: The complete drug reference]] | edition=34th edition | date=November 30, 2004 | publisher=Pharmaceutical Press | location=London | isbn= 0-85369-550-4}}</ref> It is commonly marketed to medical agencies under the [[trade name]] '''Omnopon'''.
-'''Papaveretum''' ([[British Approved Name|BAN]]) is a preparation containing a mixture of [[hydrochloride]] salts of [[opium]] [[alkaloid]]s. Since 1993, papaveretum has been defined in the [[British Pharmacopoeia]] (BP) as a mixture of 253 parts [[morphine|morphine hydrochloride]], 23 parts [[papaverine|papaverine hydrochloride]], and 20 parts [[codeine|codeine hydrochloride]] (Sweetman, 2004). It is commonly marketed under the [[trade name]] '''Omnopon&reg;'''.
+Although the use of papaveretum is now relatively uncommon following the wide availability of single-component [[opiate]]s and synthetic [[opioid]]s (e.g. [[pethidine]]) it is still used to relieve moderate to severe pain and for pre-operative sedation. In clinical settings, papaveretum is usually administered to patients via [[Subcutaneous injection|subcutaneous]], [[intramuscular]] or [[intravenous]] routes. Additionally, the morphine [[syrette]]s found in combat medical kits issued to military personnel actually contain omnopon.
-Although relatively uncommon, with the wide availability of single-component [[opiate]]s and synthetic [[opioid]]s, papaveretum is still used for moderate to severe pain and for pre-operative sedation. In the clinical setting, papaveretum is usually given by the [[subcutaneous]], [[intramuscular]] or [[intravenous]] routes.
-Prior to 1993, the preparation also contained [[noscapine]], however this was removed from the BP formulation due to the [[genotoxic]] potential of noscapine.
+Prior to 1993, papaveretum also contained [[noscapine]], though this component was removed from the BP formulation due to the [[genotoxic]] potential of noscapine.
-==See also==
-*[[Morphine]]
-*[[Papaverine]]
-*[[Codeine]]
-==External links==
-* {{ATC|N02|AA10}}
 ==References==
-* {{cite book | editor= Edited by Sean C. Sweetman | title=[[Martindale: The complete drug reference]] | edition=34th edition | date=November 30, 2004 | publisher=Pharmaceutical Press | location=London | id= ISBN 0-85369-550-4}}
+{{Reflist|2}}
-[[Category:Opioids]]
-[[Category:Drugs]]
-{{WikiDoc Help Menu}}
+[[Category:Opiate]]
-{{WikiDoc Sources}}
+[[Category:Drug]]

Papaveretum: Difference between revisions

Latest revision as of 16:30, 11 April 2015

Overview

References

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