Papaveretum: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Robot: Automated text replacement (-{{SIB}} +, -{{EH}} +, -{{EJ}} +, -{{Editor Help}} +, -{{Editor Join}} +))
No edit summary
Line 1: Line 1:
{{CMG}}
{{Drugbox
| type              = combo
| component1        = Morphine
| class1            = [[Opioid analgesic]]
| component2        = Papaverine
| class2            = [[Antispasmodic]]
| component3        = Codeine
| class3            = Opioid analgesic


<!-- Clinical data -->
| tradename        = Omnopon
| Drugs.com        =
| MedlinePlus      =
| pregnancy_AU      = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      = <!-- A / B            / C / D / X -->
| pregnancy_category=
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status      =
| routes_of_administration =


<!-- Identifiers -->
| CAS_number        =
| ATCvet            =
| ATC_prefix        = N02
| ATC_suffix        = AA10
| PubChem          = 24840907
| DrugBank          =
}}
'''Papaveretum''' ([[British Approved Name|BAN]]) is a preparation containing a mixture of [[hydrochloride]] salts of [[opium]] [[alkaloid]]s. Since 1993, papaveretum has been defined in the [[British Pharmacopoeia]] (BP) as a mixture of 253 parts [[morphine|morphine hydrochloride]], 23 parts [[papaverine|papaverine hydrochloride]], and 20 parts [[codeine|codeine hydrochloride]].<ref>{{cite book | editor= Edited by Sean C. Sweetman | title=[[Martindale: The complete drug reference]] | edition=34th edition | date=November 30, 2004 | publisher=Pharmaceutical Press | location=London | isbn= 0-85369-550-4}}</ref> It is commonly marketed to medical agencies under the [[trade name]] '''Omnopon'''.


==Overview==
Although the use of papaveretum is now relatively uncommon following the wide availability of single-component [[opiate]]s and synthetic [[opioid]]s (e.g. [[pethidine]]) it is still used to relieve moderate to severe pain and for pre-operative sedation. In clinical settings, papaveretum is usually administered to patients via [[Subcutaneous injection|subcutaneous]], [[intramuscular]] or [[intravenous]] routes. Additionally, the morphine [[syrette]]s found in combat medical kits issued to military personnel actually contain omnopon.


'''Papaveretum''' ([[British Approved Name|BAN]]) is a preparation containing a mixture of [[hydrochloride]] salts of [[opium]] [[alkaloid]]s. Since 1993, papaveretum has been defined in the [[British Pharmacopoeia]] (BP) as a mixture of 253 parts [[morphine|morphine hydrochloride]], 23 parts [[papaverine|papaverine hydrochloride]], and 20 parts [[codeine|codeine hydrochloride]] (Sweetman, 2004). It is commonly marketed under the [[trade name]] '''Omnopon&reg;'''.
Prior to 1993, papaveretum also contained [[noscapine]], though this component was removed from the BP formulation due to the [[genotoxic]] potential of noscapine.
 
Although relatively uncommon, with the wide availability of single-component [[opiate]]s and synthetic [[opioid]]s, papaveretum is still used for moderate to severe pain and for pre-operative sedation. In the clinical setting, papaveretum is usually given by the [[subcutaneous]], [[intramuscular]] or [[intravenous]] routes.
 
Prior to 1993, the preparation also contained [[noscapine]], however this was removed from the BP formulation due to the [[genotoxic]] potential of noscapine.
 
==See also==
*[[Morphine]]
*[[Papaverine]]
*[[Codeine]]
 
==External links==
* {{ATC|N02|AA10}}


==References==
==References==
* {{cite book | editor= Edited by Sean C. Sweetman | title=[[Martindale: The complete drug reference]] | edition=34th edition | date=November 30, 2004 | publisher=Pharmaceutical Press | location=London | id= ISBN 0-85369-550-4}}
{{Reflist|2}}
 


[[Category:Opioids]]
[[Category:Drugs]]


{{Opioidergics}}


{{WikiDoc Help Menu}}
[[Category:Opiates]]
{{WikiDoc Sources}}

Revision as of 16:28, 11 April 2015

Papaveretum
Combination of
MorphineOpioid analgesic
PapaverineAntispasmodic
CodeineOpioid analgesic
[[{{{component4}}}]]? Class
[[{{{component5}}}]]? Class
Clinical data
Trade namesOmnopon
ATC code
Identifiers
PubChem CID
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).

Papaveretum (BAN) is a preparation containing a mixture of hydrochloride salts of opium alkaloids. Since 1993, papaveretum has been defined in the British Pharmacopoeia (BP) as a mixture of 253 parts morphine hydrochloride, 23 parts papaverine hydrochloride, and 20 parts codeine hydrochloride.[1] It is commonly marketed to medical agencies under the trade name Omnopon.

Although the use of papaveretum is now relatively uncommon following the wide availability of single-component opiates and synthetic opioids (e.g. pethidine) it is still used to relieve moderate to severe pain and for pre-operative sedation. In clinical settings, papaveretum is usually administered to patients via subcutaneous, intramuscular or intravenous routes. Additionally, the morphine syrettes found in combat medical kits issued to military personnel actually contain omnopon.

Prior to 1993, papaveretum also contained noscapine, though this component was removed from the BP formulation due to the genotoxic potential of noscapine.

References

  1. ↑ Edited by Sean C. Sweetman, ed. (November 30, 2004). Martindale: The complete drug reference (34th edition ed.). London: Pharmaceutical Press. ISBN 0-85369-550-4.


Retrieved from "https://www.wikidoc.org/index.php?title=Papaveretum&oldid=1086299"