Pancreatic cancer diagnostic study of choice
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The diagnostic study of choice for pancreatic cancer is the dynamic spiral CT scan with contrast media (oral and IV) enhancement. Findings on CT scan that may be suggestive of pancreatic cancer include morphological changes of the gland, destruction of the peripancreatic fat and loss of the sharp margins with surrounding structures, involvement of the regional lymph nodes and adjacent vasculature, pancreatic ductal dilatation, pancreatic atrophy and obstruction of the common bile duct . CT scan is also used for the staging of pancreatic cancer.
Diagnostic Study of Choice
Gold standard/Study of choice:
- The dynamic spiral CT scan with contrast media(oral and IV) enhancement is the gold standard test for the diagnosis and staging of pancreatic cancer.
- Morphological changes of the gland
- Destruction of the peripancreatic fat and loss of the sharp margins with surrounding structures
- Involvement of the regional lymph nodes and adjacent vasculature
- Pancreatic ductal dilatation
- Pancreatic atrophy
- Obstruction of the common bile duct (CBD)
- MDCT (Multi-detector row computed tomography) the imaging modality widely used in suspected pancreatic cancer patients as the pre-operative examination. 
- MDCT is used as the primary imaging modality, and is used in conjunction with PET/CT. MDCT helps in local and distant disease assessment in a single scan. 
- MDCT is useful in the evaluation of vascular involvement, which helps in predicting the tumor resectability.
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