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Coronary artery revascularization with [[saphenous veins]] ([[saphenous vein grafts]] or [[SVGs]]) has become a modern surgical standard for the treatment of [[coronary artery disease]].  This technique can be employed when a native [[coronary artery]] is blocked, thus causing a reduction or obstruction in [[blood flow]].  [[Cardiac surgeons]] use the sutured graft to provide a connection between the [[aorta]] and the coronary artery beyond the area of obstruction, so that [[blood flow]] may resume.   
Coronary artery revascularization with [[saphenous veins]] ([[saphenous vein grafts]] or [[SVGs]]) has become a modern surgical standard for the treatment of [[coronary artery disease]].  This technique can be employed when a native [[coronary artery]] is blocked, thus causing a reduction or obstruction in [[blood flow]].  [[Cardiac surgeons]] use the sutured graft to provide a connection between the [[aorta]] and the coronary artery beyond the area of obstruction, so that [[blood flow]] may resume.   


Despite their ability to restore [[blood flow]], SVG [[stenosis]] is a common problem.  Its incidence is 15-30% one year after surgery, and it increases to 50% 10 years after surgery.
Despite their ability to restore [[blood flow]], SVG [[stenosis]] is a problem that is commonly encountered.  Its incidence is 15-30% one year after surgery, and it increases to 50% 10 years after surgery.  Several factors contribute to [[stenosis]] of [[saphenous vein grafts]], including [[intimal hyperplasia]], [[plaque]] formation, and graft remodeling.  Additionally, arterialization of the graft accelerates [[atherosclerosis]].


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Revision as of 15:10, 18 May 2010

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Background

Coronary artery revascularization with saphenous veins (saphenous vein grafts or SVGs) has become a modern surgical standard for the treatment of coronary artery disease. This technique can be employed when a native coronary artery is blocked, thus causing a reduction or obstruction in blood flow. Cardiac surgeons use the sutured graft to provide a connection between the aorta and the coronary artery beyond the area of obstruction, so that blood flow may resume.

Despite their ability to restore blood flow, SVG stenosis is a problem that is commonly encountered. Its incidence is 15-30% one year after surgery, and it increases to 50% 10 years after surgery. Several factors contribute to stenosis of saphenous vein grafts, including intimal hyperplasia, plaque formation, and graft remodeling. Additionally, arterialization of the graft accelerates atherosclerosis.

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