Oxaflozane

Jump to navigation Jump to search
Oxaflozane
Clinical data
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC14H18F3NO
Molar mass273.29 g/mol
3D model (JSmol)

WikiDoc Resources for Oxaflozane

Articles

Most recent articles on Oxaflozane

Most cited articles on Oxaflozane

Review articles on Oxaflozane

Articles on Oxaflozane in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Oxaflozane

Images of Oxaflozane

Photos of Oxaflozane

Podcasts & MP3s on Oxaflozane

Videos on Oxaflozane

Evidence Based Medicine

Cochrane Collaboration on Oxaflozane

Bandolier on Oxaflozane

TRIP on Oxaflozane

Clinical Trials

Ongoing Trials on Oxaflozane at Clinical Trials.gov

Trial results on Oxaflozane

Clinical Trials on Oxaflozane at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Oxaflozane

NICE Guidance on Oxaflozane

NHS PRODIGY Guidance

FDA on Oxaflozane

CDC on Oxaflozane

Books

Books on Oxaflozane

News

Oxaflozane in the news

Be alerted to news on Oxaflozane

News trends on Oxaflozane

Commentary

Blogs on Oxaflozane

Definitions

Definitions of Oxaflozane

Patient Resources / Community

Patient resources on Oxaflozane

Discussion groups on Oxaflozane

Patient Handouts on Oxaflozane

Directions to Hospitals Treating Oxaflozane

Risk calculators and risk factors for Oxaflozane

Healthcare Provider Resources

Symptoms of Oxaflozane

Causes & Risk Factors for Oxaflozane

Diagnostic studies for Oxaflozane

Treatment of Oxaflozane

Continuing Medical Education (CME)

CME Programs on Oxaflozane

International

Oxaflozane en Espanol

Oxaflozane en Francais

Business

Oxaflozane in the Marketplace

Patents on Oxaflozane

Experimental / Informatics

List of terms related to Oxaflozane

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Oxaflozane (Conflictan) is an antidepressant and anxiolytic drug that was introduced in France in 1982 by Solvay for the treatment of depression, but has since been abandoned.[1][2] It is a prodrug to N-dealkyloxaflozane, which acts as a non-selective serotonin receptor agonist for the 5-HT1A (pKi = 7.1), 5-HT2A (pKi = 6.0), and 5-HT2C (pKi = 7.5) subtypes.[3] Oxaflozane may also have anticholinergic effects in high doses.[4]

References

  1. Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. p. 766. ISBN 3-88763-075-0.
  2. Sittig, Marshall (1988). Pharmaceutical manufacturing encyclopedia. Park Ridge, N.J., U.S.A: Noyes Publications. p. 1122. ISBN 0-8155-1144-2.
  3. Leysen DC (February 1999). "Selective 5-HT2C agonists as potential antidepressants". IDrugs : the Investigational Drugs Journal. 2 (2): 109–20. PMID 16160946.
  4. Dutertre JP, Barbier P, Suc AL, Jonville AP, Autret E (1992). "Oxaflozane overdose in a child". Journal of Toxicology. Clinical Toxicology. 30 (1): 123–6. doi:10.3109/15563659208994452. PMID 1542141.

Template:Anxiolytics Template:Phenethylamines