Osteosarcoma x ray
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief: Mohammadmain Rezazadehsaatlou[2].
Osteosarcoma Microchapters |
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Overview
Plain radiography in primary, posteroanterior (PA), and lateral chest views are necessary. On x-ray, osteosarcoma is characterized by medullary and cortical bone destruction, periosteal reaction, tumor matrix calcification, and soft tissue mass.[1]
X Ray [2][3][4]
Conventional radiography continues to play an important role in diagnosis of osteosarcoma. Typical appearances of conventional high grade osteosarcoma include:[1]
- Medullary and cortical bone destruction.
- Wide zone of transition, permeative or moth-eaten appearance.
- Aggressive periosteal reaction characterized by:
- Sunburst appearance
- Codman triangle
- Lamellated (onion skin) reaction: less frequently seen
- Soft-tissue mass.
- Tumor matrix ossification/calcification.
- Variable: reflects a combination of the amount of tumor bone production, calcified matrix, and osteoid.
- Ill-defined fluffy or cloud-like cf. to the rings and arcs of chondroid lesions.
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Osteosarcoma of distal femur[5] . http://radiopaedia.org/articles/osteosarcoma
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Osteosarcoma of distal femur lateral view[5] . http://radiopaedia.org/articles/osteosarcoma
- The following table illustrates the findings on x-ray for the subtypes of osteosarcoma:[1]
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References
- ↑ 1.0 1.1 1.2 Osteosarcoma. Dr Amir Rezaee ◉ and Dr Frank Gaillard ◉ et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/osteosarcoma
- ↑ Yamagishi N, Miyakoshi J, Takebe H (April 1997). "Decrease in the frequency of X-ray-induced mutation by wild-type p53 protein in human osteosarcoma cells". Carcinogenesis. 18 (4): 695–700. PMID 9111202.
- ↑ Mori K, Sekine N, Sato H, Shimao D, Shiwaku H, Hyodo K, Sugiyama H, Ando M, Ohashi K, Koyama M, Nakajima Y (May 2002). "Application of synchrotron X-ray imaging to phase objects in orthopedics". J Synchrotron Radiat. 9 (Pt 3): 143–7. PMID 11972368.
- ↑ Takahashi T, Ogawa Y, Kobayashi T, Sonobe H, Seguchi H, Tani T, Yoshida S (May 2004). "The role of selective COX-2 inhibitors in reactive oxygen species formation in osteosarcoma cells after X-ray irradiation". Int. J. Mol. Med. 13 (5): 661–4. PMID 15067366.
- ↑ 5.0 5.1 Image courtesy of Dr Frank Gaillard. Radiopaedia (original file [1]). http://radiopaedia.org/licence Creative Commons BY-SA-NC