Osteosarcoma x ray: Difference between revisions
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Plain radiography in primary, posteroanterior (PA), and lateral chest views are necessary. On x-ray, osteosarcoma is characterized by [[medullary]] and [[cortical bone]] destruction, [[periosteal reaction]], tumor matrix [[calcification]], and soft tissue mass.<ref name="radio2">Osteosarcoma. Dr Amir Rezaee ◉ and Dr Frank Gaillard ◉ et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/osteosarcoma</ref> | Plain radiography in primary, posteroanterior (PA), and lateral chest views are necessary. On x-ray, osteosarcoma is characterized by [[medullary]] and [[cortical bone]] destruction, [[periosteal reaction]], tumor matrix [[calcification]], and soft tissue mass.<ref name="radio2">Osteosarcoma. Dr Amir Rezaee ◉ and Dr Frank Gaillard ◉ et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/osteosarcoma</ref> | ||
==X Ray== | ==X Ray <ref name="pmid9111202">{{cite journal |vauthors=Yamagishi N, Miyakoshi J, Takebe H |title=Decrease in the frequency of X-ray-induced mutation by wild-type p53 protein in human osteosarcoma cells |journal=Carcinogenesis |volume=18 |issue=4 |pages=695–700 |date=April 1997 |pmid=9111202 |doi= |url=}}</ref><ref name="pmid11972368">{{cite journal |vauthors=Mori K, Sekine N, Sato H, Shimao D, Shiwaku H, Hyodo K, Sugiyama H, Ando M, Ohashi K, Koyama M, Nakajima Y |title=Application of synchrotron X-ray imaging to phase objects in orthopedics |journal=J Synchrotron Radiat |volume=9 |issue=Pt 3 |pages=143–7 |date=May 2002 |pmid=11972368 |doi= |url=}}</ref><ref name="pmid15067366">{{cite journal |vauthors=Takahashi T, Ogawa Y, Kobayashi T, Sonobe H, Seguchi H, Tani T, Yoshida S |title=The role of selective COX-2 inhibitors in reactive oxygen species formation in osteosarcoma cells after X-ray irradiation |journal=Int. J. Mol. Med. |volume=13 |issue=5 |pages=661–4 |date=May 2004 |pmid=15067366 |doi= |url=}}</ref>== | ||
Conventional radiography continues to play an important role in diagnosis of osteosarcoma. Typical appearances of conventional high grade osteosarcoma include:<ref name="radio2">Osteosarcoma. Dr Amir Rezaee ◉ and Dr Frank Gaillard ◉ et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/osteosarcoma</ref> | Conventional radiography continues to play an important role in diagnosis of osteosarcoma. Typical appearances of conventional high grade osteosarcoma include:<ref name="radio2">Osteosarcoma. Dr Amir Rezaee ◉ and Dr Frank Gaillard ◉ et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/osteosarcoma</ref> | ||
*[[Medullary]] and [[cortical bone]] destruction. | *[[Medullary]] and [[cortical bone]] destruction. |
Revision as of 09:58, 3 April 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief: Mohammadmain Rezazadehsaatlou[2].
Osteosarcoma Microchapters |
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Osteosarcoma x ray On the Web |
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Overview
Plain radiography in primary, posteroanterior (PA), and lateral chest views are necessary. On x-ray, osteosarcoma is characterized by medullary and cortical bone destruction, periosteal reaction, tumor matrix calcification, and soft tissue mass.[1]
X Ray [2][3][4]
Conventional radiography continues to play an important role in diagnosis of osteosarcoma. Typical appearances of conventional high grade osteosarcoma include:[1]
- Medullary and cortical bone destruction.
- Wide zone of transition, permeative or moth-eaten appearance.
- Aggressive periosteal reaction characterized by:
- Sunburst appearance
- Codman triangle
- Lamellated (onion skin) reaction: less frequently seen
- Soft-tissue mass.
- Tumor matrix ossification/calcification.
- Variable: reflects a combination of the amount of tumor bone production, calcified matrix, and osteoid.
- Ill-defined fluffy or cloud-like cf. to the rings and arcs of chondroid lesions.
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Osteosarcoma of distal femur[5] . http://radiopaedia.org/articles/osteosarcoma
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Osteosarcoma of distal femur lateral view[5] . http://radiopaedia.org/articles/osteosarcoma
- The following table illustrates the findings on x-ray for the subtypes of osteosarcoma:[1]
Subtype | X-Ray findings |
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References
- ↑ 1.0 1.1 1.2 Osteosarcoma. Dr Amir Rezaee ◉ and Dr Frank Gaillard ◉ et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/osteosarcoma
- ↑ Yamagishi N, Miyakoshi J, Takebe H (April 1997). "Decrease in the frequency of X-ray-induced mutation by wild-type p53 protein in human osteosarcoma cells". Carcinogenesis. 18 (4): 695–700. PMID 9111202.
- ↑ Mori K, Sekine N, Sato H, Shimao D, Shiwaku H, Hyodo K, Sugiyama H, Ando M, Ohashi K, Koyama M, Nakajima Y (May 2002). "Application of synchrotron X-ray imaging to phase objects in orthopedics". J Synchrotron Radiat. 9 (Pt 3): 143–7. PMID 11972368.
- ↑ Takahashi T, Ogawa Y, Kobayashi T, Sonobe H, Seguchi H, Tani T, Yoshida S (May 2004). "The role of selective COX-2 inhibitors in reactive oxygen species formation in osteosarcoma cells after X-ray irradiation". Int. J. Mol. Med. 13 (5): 661–4. PMID 15067366.
- ↑ 5.0 5.1 Image courtesy of Dr Frank Gaillard. Radiopaedia (original file [1]). http://radiopaedia.org/licence Creative Commons BY-SA-NC