Oligodendroglioma: Difference between revisions

	Oligodendroglioma Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Oligodendroglioma from other Diseases
Epidemiology & Demographics
Risk Factors
Screening
Natural History, Complications, and Prognosis
Diagnosis
Staging
History & Symptoms
Physical Examination
Laboratory Findings
Chest X Ray
CT
MRI
Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Oligodendroglioma On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Oligodendroglioma All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Oligodendroglioma
CDC on Oligodendroglioma
Oligodendroglioma in the news
Blogs on Oligodendroglioma
Directions to Hospitals Treating Oligodendroglioma
Risk calculators and risk factors for Oligodendroglioma

VisualWikitext

Revision as of 23:21, 29 April 2019

For patient information click here.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]Michael Maddaleni, B.S., Sujit Routray, M.D. [3]

Synonyms and keywords: Oligodendroglial tumor; oligodendroglial neoplasm; neoplasm of the oligodendroglia; oligodendroglial cancer; cancer of the oligodendroglia; oligodendroma; OD; ODs; oligoastroglioma; oligodendroblastoma

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Oligodendroglioma from other Diseases

Epidemiology & Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Diagnosis

Treatment

Case Studies

Case #1

Template:Nervous tissue tumors

Template:WikiDoc Sources

@@ Line 1: / Line 1: @@
+__NOTOC__
 '''For patient information click [[{{PAGENAME}} (patient information)|here]]'''.
-{{Infobox_Disease |
-  Name           = {{PAGENAME}} |
-  Image          = |
-  Caption        = |
-  DiseasesDB     = 29450 |
-  ICD10          = C71 |
-  ICD9           = {{ICD9|191.9}} |
-  ICDO           = 9450/3-9451/3 |
-  OMIM           = |
-  MedlinePlus    = |
-  MeshID         = D009837 |
-}}
 {{Oligodendroglioma}}
-{{CMG}}
+{{CMG}}{{AE}}{{S.M.}}{{MJM}}, {{SR}}
-{{EH}}
+{{SK}} Oligodendroglial tumor; oligodendroglial neoplasm; neoplasm of the oligodendroglia; oligodendroglial cancer; cancer of the oligodendroglia; oligodendroma; OD; ODs; oligoastroglioma; oligodendroblastoma
 ==[[Oligodendroglioma overview|Overview]]==
 ==[[Oligodendroglioma historical perspective|Historical Perspective]]==
+==[[Oligodendroglioma classification|Classification]]==
 ==[[Oligodendroglioma pathophysiology|Pathophysiology]]==
+==[[Oligodendroglioma causes|Causes]]==
+==[[Oligodendroglioma differential diagnosis|Differentiating Oligodendroglioma from other Diseases]]==
 ==[[Oligodendroglioma epidemiology and demographics|Epidemiology & Demographics]]==
@@ Line 30: / Line 24: @@
 ==[[Oligodendroglioma screening|Screening]]==
-==[[Oligodendroglioma causes|Causes]]==
+==[[Oligodendroglioma natural history, complications, and prognosis|Natural History, Complications, and Prognosis]]==
-==[[Oligodendroglioma differential diagnosis|Differentiating Oligodendroglioma]]==
-==[[Oligodendroglioma natural history|Complications & Prognosis]]==
 ==Diagnosis==
-[[Oligodendroglioma history and symptoms|History and Symptoms]] | [[Oligodendroglioma physical examination|Physical Examination]] | [[Oligodendroglioma staging|Staging]] | [[Oligodendroglioma laboratory tests|Laboratory tests]] | [[Oligodendroglioma electrocardiogram|Electrocardiogram]]  | [[Oligodendroglioma x ray|X Rays]] | [[Oligodendroglioma CT|CT]] | [[Oligodendroglioma MRI|MRI]] [[Oligodendroglioma echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Oligodendroglioma other imaging findings|Other images]] | [[Oligodendroglioma other diagnostic studies|Alternative diagnostics]]
+[[Oligodendroglioma staging|Staging]] | [[Oligodendroglioma history and symptoms|History and Symptoms]] | [[Oligodendroglioma physical examination|Physical Examination]] | [[Oligodendroglioma laboratory tests|Laboratory Findings]] | [[Oligodendroglioma chest x ray|Chest X Ray]] | [[Oligodendroglioma CT|CT]] | [[Oligodendroglioma MRI|MRI]] | [[Oligodendroglioma ultrasound|Ultrasound]] | [[Oligodendroglioma other imaging findings|Other Imaging Findings]] | [[Oligodendroglioma other diagnostic studies|Other Diagnostic Studies]]
 ==Treatment==
-[[Oligodendroglioma medical therapy|Medical therapy]] | [[Oligodendroglioma surgery|Surgical options]] | [[Oligodendroglioma primary prevention|Primary prevention]]  | [[Oligodendroglioma secondary prevention|Secondary prevention]] | [[Oligodendroglioma cost-effectiveness of therapy|Financial costs]] | [[Oligodendroglioma future or investigational therapies|Future therapies]]
+[[Oligodendroglioma medical therapy|Medical therapy]] | [[Oligodendroglioma surgery|Surgery]] | [[Oligodendroglioma primary prevention|Primary Prevention]] | [[Oligodendroglioma secondary prevention|Secondary Prevention]] | [[Oligodendroglioma cost-effectiveness of therapy|Cost-Effeciveness of Therapy]] | [[Oligodendroglioma future or investigational therapies|Future or Investigational Therapies]]
-==Prognosis & treatment==
-Oligodendrogliomas are generally felt to be incurable using current treatments.  However compared to the more common [[astrocytomas]], they are slowly growing with prolonged survival.  In one series, [[median]] survival times for oligodendrogliomas were 11.6 years for grade II and 3.5 years for grade III.<ref> Ohgaki H, Kleihues P. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15977639&query_hl=10&itool=pubmed_docsum Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas.] ''J Neuropathol Exp Neurol''. 2005 Jun;64(6):479-89. PMID: 15977639</ref>  Because of the indolent nature of these tumors and the potential [[morbidity]] associated with [[neurosurgery]], [[chemotherapy]] and [[radiation therapy]], most [[oncology|neurooncologists]] will initially pursue a course of [[watchful waiting]] and treat patients symptomatically.  Symptomatic treatment often includes the use of [[anticonvulsants]] for seizures and [[Glucocorticoid|steroids]] for [[oedema|brain swelling]].  PCV chemotherapy ([[Procarbazine]], [[Lomustine|CCNU]] and [[Vincristine]]) has been shown to be effective and is currently the most commonly used chemotherapy regimen used for treating anaplastic oligodendrogliomas.<ref>Herbert H. Engelhard, M.D., Ph.D., Ana Stelea, M.D., and Arno Mundt, M.D.[http://www.virtualtrials.com/pdf/oligo.pdf] p.452</ref> [[Temozolomide]] is a common chemotheraputic drug to which oligodendrogliomas appear to be quite sensitive.  It is often used as a first line therapy.
-Because of their diffusely infiltrating nature, oligodendrogliomas cannot be completely resected and are not curable by [[surgery|surgical excision]].  If the tumor mass compresses adjacent brain structures, a [[neurosurgery|neurosurgeon]] will typically remove as much of the tumor as he or she can without damaging other critical, healthy brain structures. Surgery may be followed up by [[chemotherapy]], [[radiation]], or a mix of both. Oligodendrogliomas, like all other infiltrating [[gliomas]], have a very high (almost uniform) rate of recurrence and gradually increase in grade over time.  Recurrent tumors are generally treated with more aggressive chemotherapy and radiation therapy. Recently, [[stereotactic surgery]] has proven successful in treating small tumors that have been diagnosed early.
-Long-term survival is reported in a minority of patients.<ref>Tatter SB. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=12392640&query_hl=7&itool=pubmed_DocSum Recurrent malignant glioma in adults.] ''Curr Treat Options Oncol''. 2002 Dec;'''3'''(6):509-24. PMID: 12392640,</ref> With aggressive treatment and close monitoring, it is possible to outlive the typical life expectancies for both low grade and high grade oligodendrogliomas. In rare cases, patients have survived for up to fifteen years post-diagnosis. Westergaard’s
-study (1997) showed that patients younger than 20 years had a median survival of 17.5 years.<ref>Herbert H. Engelhard, M.D., Ph.D., Ana Stelea, M.D., and Arno Mundt, M.D.[http://www.virtualtrials.com/pdf/oligo.pdf] p.449</ref> Another study shows a 34% survival rate after 20 years. <ref> {{cite journal |author=Feigenberg SJ, Amdur RJ, Morris CG, Mendenhall WM, Marcus RB, Friedman WA |title=Oligodendroglioma: does deferring treatment compromise outcome? |journal=Am. J. Clin. Oncol. |volume=26 |issue=3 |pages=e60-6 |year=2003 |pmid=12796617 |doi=10.1097/01.COC.0000072507.25834.D6}}</ref>
-==References==
+==Case Studies==
-{{Reflist|2}}
+[[Oligodendroglioma case study one|Case #1]]
 {{Nervous tissue tumors}}
-{{SIB}}
-[[de:Oligodendrogliom]]
-{{WikiDoc Help Menu}}
-{{WikiDoc Sources}}
 [[Category:Neurological disorders]]
 [[Category:Types of cancer]]
 [[Category:Neurosurgery]]
-[[Category:Oncology]]
 [[Category:Disease]]
 [[Category:Mature chapter]]
+[[Category:Oncology]]
+{{WikiDoc Help Menu}}
+{{WikiDoc Sources}}
+ [[Category:Up-To-Date]]
+[[Category:Oncology]]
+[[Category:Medicine]]
+[[Category:Neurology]]
+[[Category:Neurosurgery]]

Oligodendroglioma: Difference between revisions

Revision as of 23:21, 29 April 2019

Diagnosis

Treatment

Case Studies

Navigation menu