OR4F4

Olfactory receptor, family 4, subfamily F, member 4
Identifiers
Symbols	OR4F4 ; OLA-7501; OR4F18; OR4F11P; OR4F19
External IDs	HomoloGene: 88410
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Olfactory receptor, family 4, subfamily F, member 4, also known as OR4F4, is a human gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Trask BJ, Friedman C, Martin-Gallardo A; et al. (1998). "Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes". Hum. Mol. Genet. 7 (1): 13–26. PMID 9384599.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mefford HC, Linardopoulou E, Coil D; et al. (2002). "Comparative sequencing of a multicopy subtelomeric region containing olfactory receptor genes reveals multiple interactions between non-homologous chromosomes". Hum. Mol. Genet. 10 (21): 2363–72. PMID 11689483.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Linardopoulou E, Mefford HC, Nguyen O; et al. (2002). "Transcriptional activity of multiple copies of a subtelomerically located olfactory receptor gene that is polymorphic in number and location". Hum. Mol. Genet. 10 (21): 2373–83. PMID 11689484.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fuchs T, Malecova B, Linhart C; et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. PMID 12213199.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052.CS1 maint: Multiple names: authors list (link)

External links

• OR4F4+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.