OR1E1

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Olfactory receptor, family 1, subfamily E, member 1
Identifiers
Symbols OR1E1 ; OR17-2; HGM071; OR13-66; OR17-32; OR1E5; OR1E6; OR1E8P; OR1E9P; OST547
External IDs Template:MGI HomoloGene73918
RNA expression pattern
File:PBB GE OR1E1 208587 s at tn.png
File:PBB GE OR1E1 214515 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Olfactory receptor, family 1, subfamily E, member 1, also known as OR1E1, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

See also

References

  1. 1.0 1.1 "Entrez Gene: OR1E1 olfactory receptor, family 1, subfamily E, member 1".

Further reading

  • Parmentier M, Libert F, Schurmans S; et al. (1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. doi:10.1038/355453a0. PMID 1370859.
  • Ben-Arie N, Lancet D, Taylor C; et al. (1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire". Hum. Mol. Genet. 3 (2): 229–35. PMID 8004088.
  • Rouquier S, Taviaux S, Trask BJ; et al. (1998). "Distribution of olfactory receptor genes in the human genome". Nat. Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546.
  • Glusman G, Sosinsky A, Ben-Asher E; et al. (2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics. 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID 10673334.
  • Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. doi:10.1073/pnas.040580197. PMID 10706615.
  • Fuchs T, Malecova B, Linhart C; et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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