Non-alcoholic fatty liver disease: Difference between revisions

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__NOTOC__
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{{Non alcoholic fatty liver disease}}
{{Non alcoholic fatty liver disease}}
'''Editor in Chief''': Elliot Tapper, M.D., Beth Israel Deaconess Medical Center
{{CMG}}; {{AE}} {{VKG}}


'''For the patient information page on this topic, click [[non-alcoholic fatty liver disease (patient information)|here]].'''
'''For the patient information page on this topic, click [[non-alcoholic fatty liver disease (patient information)|here]].'''


{{SK}} NASH, NAFLD, non alcoholic steatohepatitis
{{SK}} NASH, NAFLD, non-alcoholic steatohepatitis


==[[Non-alcoholic fatty liver disease overview|Overview]]==
==[[Non-alcoholic fatty liver disease overview|Overview]]==
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==[[Non-alcoholic fatty liver disease natural history, complications and prognosis|Natural History, Complications, and Prognosis]]==
==[[Non-alcoholic fatty liver disease natural history, complications and prognosis|Natural History, Complications, and Prognosis]]==
===Natural History===
*The symptoms of NAFLD usually develop in the fourth decade of life.
*With the raising concern of obesity and metabolic syndrome NAFLD is becoming the most common liver disease in the world.
*Our understanding of NAFLD natural history is evolving with extensive research and we can classify NAFLD further by prospectively collecting the data with well defined and well designed studies.  <ref name="pmid27003142">{{cite journal |vauthors=Goh GB, McCullough AJ |title=Natural History of Nonalcoholic Fatty Liver Disease |journal=Dig. Dis. Sci. |volume=61 |issue=5 |pages=1226–33 |year=2016 |pmid=27003142 |doi=10.1007/s10620-016-4095-4 |url=}}</ref>
*If left untreated, Patients with NAFLD may progress to develop NASH which is a more serious complication.
*
===Complications===
*Common complications of NAFLD include: <ref name="urlNonalcoholic Fatty Liver Disease Symptoms, Causes, and More">{{cite web |url=https://www.healthline.com/health/nonalcoholic-fatty-liver-disease#complications |title=Nonalcoholic Fatty Liver Disease Symptoms, Causes, and More |format= |work= |accessdate=}}</ref>
**NASH
**Cirrhosis
**Gastro intestinal bleeding
**Liver failure
**Liver cancer
===Prognosis===
*Prognosis is generally variable with NAFLD  patients, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
*Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
*The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
*[Subtype of disease/malignancy] is associated with the most favorable prognosis.
*The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.


==Diagnosis==
==Diagnosis==
[[Non-alcoholic fatty liver disease history and symptoms|History and Symptoms]] | [[Non-alcoholic fatty liver disease physical examination|Physical Examination]] | [[Non-alcoholic fatty liver disease laboratory findings|Laboratory Findings]] | [[Non-alcoholic fatty liver disease electrocardiogram|Electrocardiogram]] | [[Non-alcoholic fatty liver disease x ray|X Ray]] | [[Non-alcoholic fatty liver disease CT|CT]] | [[Non-alcoholic fatty liver disease MRI|MRI]] | [[Non-alcoholic fatty liver disease ultrasound|Ultrasound]] | [[Non-alcoholic fatty liver disease other imaging findings|Other Imaging Findings]] | [[Non-alcoholic fatty liver disease other diagnostic studies|Other Diagnostic Studies]]
[[Non-alcoholic fatty liver disease history and symptoms|History and Symptoms]] | [[Non-alcoholic fatty liver disease physical examination|Physical Examination]] | [[Non-alcoholic fatty liver disease laboratory findings|Laboratory Findings]] | [[Non-alcoholic fatty liver disease electrocardiogram|Electrocardiogram]] | [[Non-alcoholic fatty liver disease x ray|X Ray]] | [[Non-alcoholic fatty liver disease CT|CT]] | [[Non-alcoholic fatty liver disease MRI|MRI]] | [[Non-alcoholic fatty liver disease ultrasound|Ultrasound]] | [[Non-alcoholic fatty liver disease other imaging findings|Other Imaging Findings]] | [[Non-alcoholic fatty liver disease other diagnostic studies|Other Diagnostic Studies]] | [[Non-alcoholic fatty liver disease Noninvasive scores| Noninvasive scores]]


==Treatment==
==Treatment==

Revision as of 15:22, 22 September 2021

Non-Alcoholic Fatty Liver Disease Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

For the patient information page on this topic, click here.

Synonyms and keywords: NASH, NAFLD, non-alcoholic steatohepatitis

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Non-Alcoholic Fatty Liver Disease from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X Ray | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies | Noninvasive scores

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

External Links

  • NIH page on Nonalcoholic Steatohepatitis


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