Neuroblastoma risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]
Risk Factors
The etiology of neuroblastoma is not well understood. Several risk factors have been proposed and are the subject of ongoing research. Due to characteristic early onset many studies have focussed on parental factors around conception and during gestation. Factors investigated have included occupation (i.e. exposure to chemicals in specific industries), smoking, alcohol consumption, use of medicinal drugs during pregnancy and birth factors, however results have been inconsistent.[1]
Other studies have examined possible links with atopy and exposure to infection early in life,[2] use of hormones and fertility drugs,[3]and maternal use of hair dye.[4]
References
- ↑ Olshan, AF, Bunin, GR (2000) Epidemiology of Neuroblastoma. In: Brodeur, GM, Sawada, T, Tsuchida, Y, Voute, PA eds. , Neuroblastoma, Elsevier, Amsterdam, pp 33-39. ISBN 044450222X [1]
- ↑ Menegaux F,et al."Day Care, Childhood Infections and Risk of Neuroblastoma", Am J Epidemiol 2004; 159:843-851.
- ↑ Olshan AF,et al. "Hormone and Fertility Drug Use and the Risk of Neuroblastoma: A Report from the Children's Cancer Group and the Pediatric Oncology Group", Am J Epidemiol 1999;150:930-8.
- ↑ ,McCall EE,et al."Maternal hair dye use and risk of neuroblastoma in offspring", Cancer Causes and Control 2005; 16,6:743-8