Neuroblastoma laboratory tests: Difference between revisions
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==Overview== | ==Overview== | ||
An elevated concentration of blood and urinary [[vanillylmandelic acid]] (VMA) and [[homovanillic acid]] (HVA) is suggestive of neuroblastoma.<ref name="gov"> Neuroblastoma Treatment for health professionals. National Cancer Institute (2015) http://www.cancer.gov/types/neuroblastoma/hp/neuroblastoma-treatment-pdq#link/_534_toc Accessed on October, 7 2015</ref><ref name="wiki">Neuroblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Neuroblastoma Accessed on October, 5 2015</ref> | An elevated concentration of blood and urinary [[vanillylmandelic acid]] (VMA) and [[homovanillic acid]] (HVA) is suggestive of neuroblastoma.<ref name="gov"> Neuroblastoma Treatment for health professionals. National Cancer Institute (2015) http://www.cancer.gov/types/neuroblastoma/hp/neuroblastoma-treatment-pdq#link/_534_toc Accessed on October, 7 2015</ref><ref name="wiki">Neuroblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Neuroblastoma Accessed on October, 5 2015</ref><ref name="pmid21736987">{{cite journal| author=Colon NC, Chung DH| title=Neuroblastoma. | journal=Adv Pediatr | year= 2011 | volume= 58 | issue= 1 | pages= 297-311 | pmid=21736987 | doi=10.1016/j.yapd.2011.03.011 | pmc=PMC3668791 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21736987 }} </ref> | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
====Blood Tests==== | ====Blood Tests<ref name="gov"> Neuroblastoma Treatment for health professionals. National Cancer Institute (2015) http://www.cancer.gov/types/neuroblastoma/hp/neuroblastoma-treatment-pdq#link/_534_toc Accessed on October, 7 2015</ref><ref name="wiki">Neuroblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Neuroblastoma Accessed on October, 5 2015</ref><ref name="pmid21736987">{{cite journal| author=Colon NC, Chung DH| title=Neuroblastoma. | journal=Adv Pediatr | year= 2011 | volume= 58 | issue= 1 | pages= 297-311 | pmid=21736987 | doi=10.1016/j.yapd.2011.03.011 | pmc=PMC3668791 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21736987 }} </ref>==== | ||
* Reduced [[hemoglobin]] level | * Reduced [[hemoglobin]] level | ||
* Elevated [[ferritin]] level | * Elevated [[ferritin]] level | ||
| Line 18: | Line 18: | ||
* Elevated neuron-specific [[enolase]] level(>100 ng/ml) | * Elevated neuron-specific [[enolase]] level(>100 ng/ml) | ||
====Urinalysis==== | ====Urinalysis<ref name="gov"> Neuroblastoma Treatment for health professionals. National Cancer Institute (2015) http://www.cancer.gov/types/neuroblastoma/hp/neuroblastoma-treatment-pdq#link/_534_toc Accessed on October, 7 2015</ref><ref name="wiki">Neuroblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Neuroblastoma Accessed on October, 5 2015</ref><ref name="pmid21736987">{{cite journal| author=Colon NC, Chung DH| title=Neuroblastoma. | journal=Adv Pediatr | year= 2011 | volume= 58 | issue= 1 | pages= 297-311 | pmid=21736987 | doi=10.1016/j.yapd.2011.03.011 | pmc=PMC3668791 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21736987 }} </ref>==== | ||
* Elevated | * Elevated [[catecholamine]] levels | ||
* Elevated [[ | * Elevated [[vanillylmandelic acid]] (VMA) level | ||
* Elevated [[ | * Elevated [[homovanillic acid]] (HVA) level | ||
==References== | ==References== | ||
Revision as of 13:31, 8 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
An elevated concentration of blood and urinary vanillylmandelic acid (VMA) and homovanillic acid (HVA) is suggestive of neuroblastoma.[1][2][3]
Laboratory Findings
Blood Tests[1][2][3]
- Reduced hemoglobin level
- Elevated ferritin level
- Elevated catecholamine levels
- Elevated dopamine level
- Elevated vanillylmandelic acid (VMA) level
- Elevated homovanillic acid (HVA) level
- Elevated lactate dehydrogenase level (>1500 U/ml)
- Elevated neuron-specific enolase level(>100 ng/ml)
Urinalysis[1][2][3]
- Elevated catecholamine levels
- Elevated vanillylmandelic acid (VMA) level
- Elevated homovanillic acid (HVA) level
References
- ↑ 1.0 1.1 1.2 Neuroblastoma Treatment for health professionals. National Cancer Institute (2015) http://www.cancer.gov/types/neuroblastoma/hp/neuroblastoma-treatment-pdq#link/_534_toc Accessed on October, 7 2015
- ↑ 2.0 2.1 2.2 Neuroblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Neuroblastoma Accessed on October, 5 2015
- ↑ 3.0 3.1 3.2 Colon NC, Chung DH (2011). "Neuroblastoma". Adv Pediatr. 58 (1): 297–311. doi:10.1016/j.yapd.2011.03.011. PMC 3668791. PMID 21736987.