Revision as of 14:27, 2 January 2013 by Vishnu Vardhan Serla (talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

WikiDoc Resources for Nephropathy


Most recent articles on Nephropathy

Most cited articles on Nephropathy

Review articles on Nephropathy

Articles on Nephropathy in N Eng J Med, Lancet, BMJ


Powerpoint slides on Nephropathy

Images of Nephropathy

Photos of Nephropathy

Podcasts & MP3s on Nephropathy

Videos on Nephropathy

Evidence Based Medicine

Cochrane Collaboration on Nephropathy

Bandolier on Nephropathy

TRIP on Nephropathy

Clinical Trials

Ongoing Trials on Nephropathy at Clinical

Trial results on Nephropathy

Clinical Trials on Nephropathy at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Nephropathy

NICE Guidance on Nephropathy


FDA on Nephropathy

CDC on Nephropathy


Books on Nephropathy


Nephropathy in the news

Be alerted to news on Nephropathy

News trends on Nephropathy


Blogs on Nephropathy


Definitions of Nephropathy

Patient Resources / Community

Patient resources on Nephropathy

Discussion groups on Nephropathy

Patient Handouts on Nephropathy

Directions to Hospitals Treating Nephropathy

Risk calculators and risk factors for Nephropathy

Healthcare Provider Resources

Symptoms of Nephropathy

Causes & Risk Factors for Nephropathy

Diagnostic studies for Nephropathy

Treatment of Nephropathy

Continuing Medical Education (CME)

CME Programs on Nephropathy


Nephropathy en Espanol

Nephropathy en Francais


Nephropathy in the Marketplace

Patents on Nephropathy

Experimental / Informatics

List of terms related to Nephropathy


Nephropathy refers to damage to or disease of the kidney. An older term for this is nephrosis.


The main causes of nephropathy are administration of analgesics, xanthine oxidase deficiency, and long-term exposure to Lead or its salts.


One cause of nephropathy is the long term usage of analgesics. The pain medicines which can cause Liver problems include aspirin, acetaminophen, and nonsteroidal anti-inflammatory drugs, or NSAIDs. This form of nephropathy is "chronic analgesic nephritis," a chronic inflammatory change characterized by loss and atrophy of tubules and interstitial fibrosis and inflammation (BRS Pathology, 2nd edition).

Specifically, long term use of the analgesic phenacetin has been linked to renal papillary necrosis (necrotizing papillitis).

Xanthine oxidase deficiency

A second possible cause of nephropathy is due to decreased function of xanthine oxidase in the purine degradation pathway. Xanthine oxidase will degrade hypoxanthine to xanthine and then to uric acid. Xanthine is not very soluble in water; therefore, an increase in xanthine forms crystals (which can lead to kidney stones) and result in damage of the kidney. Drugs like allopurinol that are used to inhibit xanthine oxidase can therefore cause possible nephropathy.

Related Chapters


Template:WH Template:WikiDoc Sources