Nephrocalcinosis: Difference between revisions
No edit summary |
|||
| Line 95: | Line 95: | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
==External Links == | |||
*[http://goldminer.arrs.org/search.php?query=cortical%20nephrocalcinosis Goldminer: Cortical nephrocalcinosis] | |||
{{Nephrology}} | {{Nephrology}} | ||
Revision as of 00:18, 15 March 2009
| Nephrocalcinosis | |
 | |
|---|---|
| Medullary nephrocalcinosis. Image courtesy of RadsWiki |
|
WikiDoc Resources for Nephrocalcinosis |
|
Articles |
|---|
|
Most recent articles on Nephrocalcinosis Most cited articles on Nephrocalcinosis |
|
Media |
|
Powerpoint slides on Nephrocalcinosis |
|
Evidence Based Medicine |
|
Clinical Trials |
|
Ongoing Trials on Nephrocalcinosis at Clinical Trials.gov Trial results on Nephrocalcinosis Clinical Trials on Nephrocalcinosis at Google
|
|
Guidelines / Policies / Govt |
|
US National Guidelines Clearinghouse on Nephrocalcinosis NICE Guidance on Nephrocalcinosis
|
|
Books |
|
News |
|
Commentary |
|
Definitions |
|
Patient Resources / Community |
|
Patient resources on Nephrocalcinosis Discussion groups on Nephrocalcinosis Patient Handouts on Nephrocalcinosis Directions to Hospitals Treating Nephrocalcinosis Risk calculators and risk factors for Nephrocalcinosis
|
|
Healthcare Provider Resources |
|
Causes & Risk Factors for Nephrocalcinosis |
|
Continuing Medical Education (CME) |
|
International |
|
|
|
Business |
|
Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Contributors: Cafer Zorkun M.D., PhD.
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Overview
Nephrocalcinosis, once known as Albright's calcinosis after Fuller Albright, is a term originally used to describe deposition of calcium salts in the renal parenchyma due to hyperparathyroidism. It is now more commonly used to describe diffuse, fine, renal parenchymal calcification on radiology.[1] During its early stages, nephrocalcinosis is visible on x-ray, and appears as a fine granular mottling over the renal outlines. These outlines eventually come together to form a dense mass.[2]
It is most commonly seen as an incidental finding with medullary sponge kidney on an abdominal x-ray. However, it may be severe enough to cause (as well as be caused by) renal tubular acidosis or even end stage renal failure, due to disruption of the renal tissue by the deposited calcium.
Differential Diagnosis
Stages of nephrocalcinosis
- Chemical nephrocalcinosis
- Microscopic nephrocalcinosis
- Macroscopic nephrocalcinosis
Causes
Causes of cortical nephrocalcinosis
- Acute cortical necrosis. May be caused by:
- Chronic glomerulonephritis
- Alport syndrome
- Prolonged hypercalcemia and/or hypercalciuria
- Renal transplant rejection
- Sickle cell disease (rare)
- Vitamin B6 deficiency (pyridoxine deficiency) (rare)
Causes of medullary nephrocalcinosis
- Medullary sponge kidney
- Hyperparathyroidism
- Renal tubular acidosis (specifically distal RTA)
- Renal tuberculosis
- Renal papillary necrosis
- Hyperoxaluria
Other causes of hypercalcemia (and thus hypercalciuria)
- Immobilization (leading to hypercalcemia and hypercalciuria)
- Milk-alkali syndrome
- Hypervitaminosis D
- Sarcoidosis
Diagnostic Findings
Patient #1
Patient #2
References
- ↑ "Nephrocalcinosis". eMedicine. 2003-09-09. Retrieved 2007-03-10.
- ↑ "Albright's Nephrocalcinosis". e-radiology. Retrieved 2007-03-10.