Nephritic syndrome classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Classification

Acute nephritic syndrome may be differentiated according to the etiology of renal disease. Acute nephritis may be classified based on renal vs. non-renal etiology. Similarly, acute nephritis may be classified as idiopathic vs. secondary to other conditions. Finally, diseases may be classified according to the proliferative vs. non-proliferative changes seen on pathology.

The following tables shows the classification of acute glomerulonephritis:

Classification of Glomerular Diseases

Type of Disorder	Proliferative Changes	No Proliferative Changes
Primary Renal Disorder	IgA nephropathy IgM nephropathy Other mesangioproliferative glomerulonephritides Crescentic glomerulonephritis With immune deposits Pauci-immune Membranoproliferative glomerulonephritis	Focal segmental glomerulosclerosis Membranous glomerulopathy Minimal-change disease Thin basement membrane disease
Secondary Disorder	Lupus nephritis Post-infectious glomerulonephritis Glomerulonephritis related to hepatitis B or C Systemic vasculitides Wegener's granulomatosis Polyarteritis nodosa Henoch-Schonlein purpura Idiopathic	Diabetic nephropathy Amyloidosis Light-chain nephropathy Human immunodeficiency virus nephropathy Alport's syndrome Drug-induced glomerulopathies