Neostigmine methylsulfate
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Gloria Picoy [2]
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Overview
Neostigmine methylsulfate is a cholinesterase Inhibitor that is FDA approved for the prophylaxis of and treatment of postoperative distention and urinary retention after mechanical obstruction has been excluded, the symptomatic control of myasthenia gravis when oral therapy is impractical and reversal of effects of non-depolarizing neuromuscular blocking agents after surgery.. Common adverse reactions include {{{adverseReactions}}}.
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
There is limited information regarding Neostigmine methylsulfate FDA-Labeled Indications and Dosage (Adult) in the drug label.
Off-Label Use and Dosage (Adult)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Neostigmine methylsulfate in adult patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Neostigmine methylsulfate in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
There is limited information regarding Neostigmine methylsulfate FDA-Labeled Indications and Dosage (Pediatric) in the drug label.
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Neostigmine methylsulfate in pediatric patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Neostigmine methylsulfate in pediatric patients.
Contraindications
There is limited information regarding Neostigmine methylsulfate Contraindications in the drug label.
Warnings
There is limited information regarding Neostigmine methylsulfate Warnings' in the drug label.
Adverse Reactions
Clinical Trials Experience
There is limited information regarding Neostigmine methylsulfate Clinical Trials Experience in the drug label.
Postmarketing Experience
There is limited information regarding Neostigmine methylsulfate Postmarketing Experience in the drug label.
Drug Interactions
There is limited information regarding Neostigmine methylsulfate Drug Interactions in the drug label.
Use in Specific Populations
Pregnancy
Pregnancy Category (FDA):
There is no FDA guidance on usage of Neostigmine methylsulfate in women who are pregnant.
Pregnancy Category (AUS):
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Neostigmine methylsulfate in women who are pregnant.
Labor and Delivery
There is no FDA guidance on use of Neostigmine methylsulfate during labor and delivery.
Nursing Mothers
There is no FDA guidance on the use of Neostigmine methylsulfate in women who are nursing.
Pediatric Use
There is no FDA guidance on the use of Neostigmine methylsulfate in pediatric settings.
Geriatic Use
There is no FDA guidance on the use of Neostigmine methylsulfate in geriatric settings.
Gender
There is no FDA guidance on the use of Neostigmine methylsulfate with respect to specific gender populations.
Race
There is no FDA guidance on the use of Neostigmine methylsulfate with respect to specific racial populations.
Renal Impairment
There is no FDA guidance on the use of Neostigmine methylsulfate in patients with renal impairment.
Hepatic Impairment
There is no FDA guidance on the use of Neostigmine methylsulfate in patients with hepatic impairment.
Females of Reproductive Potential and Males
There is no FDA guidance on the use of Neostigmine methylsulfate in women of reproductive potentials and males.
Immunocompromised Patients
There is no FDA guidance one the use of Neostigmine methylsulfate in patients who are immunocompromised.
Administration and Monitoring
Administration
There is limited information regarding Neostigmine methylsulfate Administration in the drug label.
Monitoring
There is limited information regarding Neostigmine methylsulfate Monitoring in the drug label.
IV Compatibility
There is limited information regarding the compatibility of Neostigmine methylsulfate and IV administrations.
Overdosage
There is limited information regarding Neostigmine methylsulfate overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.
Pharmacology
There is limited information regarding Neostigmine methylsulfate Pharmacology in the drug label.
Mechanism of Action
There is limited information regarding Neostigmine methylsulfate Mechanism of Action in the drug label.
Structure
There is limited information regarding Neostigmine methylsulfate Structure in the drug label.
Pharmacodynamics
There is limited information regarding Neostigmine methylsulfate Pharmacodynamics in the drug label.
Pharmacokinetics
There is limited information regarding Neostigmine methylsulfate Pharmacokinetics in the drug label.
Nonclinical Toxicology
There is limited information regarding Neostigmine methylsulfate Nonclinical Toxicology in the drug label.
Clinical Studies
There is limited information regarding Neostigmine methylsulfate Clinical Studies in the drug label.
How Supplied
There is limited information regarding Neostigmine methylsulfate How Supplied in the drug label.
Storage
There is limited information regarding Neostigmine methylsulfate Storage in the drug label.
Images
Drug Images
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Package and Label Display Panel
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Patient Counseling Information
There is limited information regarding Neostigmine methylsulfate Patient Counseling Information in the drug label.
Precautions with Alcohol
Alcohol-Neostigmine methylsulfate interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
Brand Names
There is limited information regarding Neostigmine methylsulfate Brand Names in the drug label.
Look-Alike Drug Names
There is limited information regarding Neostigmine methylsulfate Look-Alike Drug Names in the drug label.
Drug Shortage Status
Price
References
The contents of this FDA label are provided by the National Library of Medicine.