Necrotizing fasciitis: Difference between revisions

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==[[Necrotizing fasciitis epidemiology and demographics|Epidemiology and Demographics]]==
==[[Necrotizing fasciitis epidemiology and demographics|Epidemiology and Demographics]]==
===Incidence===
*The incidence of necrotizing fasciitis in adults is 0.40 cases per 100,000 people/year and the incidence in children is higher at 0.08 cases per 100,000 people/year.<ref name="pmid9599907">{{cite journal| author=File TM, Tan JS, DiPersio JR| title=Group A streptococcal necrotizing fasciitis. Diagnosing and treating the "flesh-eating bacteria syndrome". | journal=Cleve Clin J Med | year= 1998 | volume= 65 | issue= 5 | pages= 241-9 | pmid=9599907 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9599907  }} </ref><ref name="pmid3051309">{{cite journal| author=Chaouat Y, Chaouat D| title=[Primary hyperparathyroidism. History]. | journal=Rev Rhum Mal Osteoartic | year= 1988 | volume= 55 | issue= 7 | pages= 475-8 | pmid=3051309 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3051309  }} </ref>
*


==[[Necrotizing fasciitis risk factors|Risk Factors]]==
==[[Necrotizing fasciitis risk factors|Risk Factors]]==

Revision as of 15:18, 29 August 2016

Necrotizing fasciitis Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Necrotizing fasciitis from other Diseases

Epidemiology and Demographics

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Diagnosis

Diagnostic Criteria

History and Symptoms

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2] Cafer Zorkun, M.D., Ph.D. [3]

Synonyms and keywords:Phagadena; Phagadena gangrenosum; Meleney’s gangrene; Hemolytic streptococcal gangrene; Flesh eating bacteria; Hospital gangrene; Acute dermal gangrene; Suppurative fasciitis; Synergistic necrotizing cellulitis; Gangrenous ulcer; Malignant ulcer; Putrid ulcer

Overview

Historical Perspective

  • Necrotizing fasciitis was first described in 1871 during civil war by a confederate army surgeon named Joseph Jones.
  • The association between bacterial infection and necrotizing fasciitis was made in 1918.
  • In 1952, the disease was named as necrotizing fasciitis.[1]

Classification

  • Necrotizing fasciitis may be classified according to international classification of diseases-10 (ICD-10) into:[2]
  • M72.6 Necrotizing fasciitis
  • Based on microbiological findings, necrotizing fasciitis may be classified into four types
  • Type 1: Polymicrobial:
  • Type 2: Group A streptococcal
  • Type 3: Gas gangrene or clostridial myonecrosis
  • Type 4:
Type Pathogens
Type 1 or Polymicrobial Staphylococcus aureus
● Haemophilus
● Vibrio
● Several other aerobic and anaerobic strains
Type 2 or Monomicrobial ● Beta hemolytic streptococcus group A (Streptococcus pyogenes)
● High spiky fever
● Firm mass with pus
Type 3 or
Gas gangrene or
Clostridial myonecrosis
● Fluctuant mass
● Dissemination of infection
Septicemia
Acute renal failure
● Metastatic abscesses
Septic shock
● Death
Type 4

Pathophysiology

Causes

Differentiating Necrotizing fasciitis from other Diseases

Epidemiology and Demographics

Incidence

  • The incidence of necrotizing fasciitis in adults is 0.40 cases per 100,000 people/year and the incidence in children is higher at 0.08 cases per 100,000 people/year.[3][4]

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X Ray | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Future or Investigational Therapies

Case Studies

Case#1

See also

Template:Diseases of the musculoskeletal system and connective tissue


Template:WikiDoc Sources

  1. Caplehorn JR, Bell J (1991). "Methadone dosage and retention of patients in maintenance treatment". Med J Aust. 154 (3): 195–9. PMID 1988793.
  2. ICD-10 version:2016. http://apps.who.int/classifications/icd10/browse/2016/en#/M72.6 2016 Accessed on August 25,2016
  3. File TM, Tan JS, DiPersio JR (1998). "Group A streptococcal necrotizing fasciitis. Diagnosing and treating the "flesh-eating bacteria syndrome"". Cleve Clin J Med. 65 (5): 241–9. PMID 9599907.
  4. Chaouat Y, Chaouat D (1988). "[Primary hyperparathyroidism. History]". Rev Rhum Mal Osteoartic. 55 (7): 475–8. PMID 3051309.