Necrolytic migratory erythema
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| Necrolytic migratory erythema |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Necrolytic migratory erythema (NME) is a classical symptom observed in patients with glucagonoma and is present in 80% of cases. Associated NME is characterized by the spread of erythematous blisters and swelling across areas subject to greater friction and pressure, including the lower abdomen, buttocks, perineum, and groin.
Diagnosis
Symptoms
It consists of serpiginous (slow progressing) erythematous plaques. Where the migratory edge has an "eroded" appearance. It usually starts in the Perineum.
- Associated symptoms
Weight loss, anemia , mild diabetes, diarrhea and glossitis are associated. Liver metastasis is often present.
References
Template:Skin and subcutaneous tissue symptoms and signs Template:Nervous and musculoskeletal system symptoms and signs Template:Urinary system symptoms and signs Template:Cognition, perception, emotional state and behaviour symptoms and signs Template:Speech and voice symptoms and signs Template:General symptoms and signs