Nasopharyngeal carcinoma secondary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]

Overview

Secondary prevention measures of nasopharyneal cancer include routine physical examination and imaging at scheduled intervals after treatment. Dental screening and screening for thyroid cancers are recommended among patients who had received radiation therapy to the oral cavity and cervical region, respectively.

Secondary Prevention

Follow up after treatment

Patients treated for nasopharyngeal carcinoma should follow-up for secondary prevention. Follow-up measures are shown in the table below:

Follow up	Description
Physical exam	Every 1-3 months for 1st year after treatment Every 2-6 months for 2nd year after treatment Every 4-8 months between 3 and 5 years after treatment Annually thereafter
Nasendoscopy	Immediately after radiation therapy
Scanning CT Scan MRI	Scans are performed at routine intervals as follows: Baseline scanning is done in 3-6 months after treatment, further scans are scheduled based on finding of physical exam and symptoms experienced by the patient Scanning for asymptomatic patients is not encouraged
Thyroid hormone testing	Thyroid stimulating hormone testing every 12 months if neck is exposed to radiation therapy
Dental screening	Only recommended if oral cavity is exposed to radiations

^{Table adapted from Pfister DG, et al. Head and neck cancers, version 2.2013. Featured updates to the NCCN guidelines. J Natl Compr Canc Netw. 2013;11(8):917-23.}

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