Nasopharyngeal carcinoma classification: Difference between revisions
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==Classification== | ==Classification== | ||
===Histologic classification=== | ===Histologic classification=== | ||
World Health Classification (2005) for NPC | World Health Classification (2005) for NPC | ||
{| class="wikitable" | {| class="wikitable" | ||
! | ! Classification | ||
! | ! Former name | ||
! Description | ! Description | ||
! EBV | ! EBV | ||
| Line 15: | Line 15: | ||
! Prognosis | ! Prognosis | ||
|- | |- | ||
| 1 | | Keratinizing | ||
|Type 1, squamous cell | |||
carcinoma | |||
| graded poorly-well-differentiated | | graded poorly-well-differentiated | ||
| -ve | | -ve | ||
| | | | ||
| | | poor | ||
|- | |- | ||
| | | Nonkeratinizing, differentiated | ||
| | |Type 2, transitional | ||
carcinoma | |||
| well defined cell borders & tumor nest borders | | well defined cell borders & tumor nest borders | ||
| +ve | | +ve | ||
| Line 29: | Line 33: | ||
| good | | good | ||
|- | |- | ||
| | | Nonkeratinizing, undifferentiated | ||
| | |Type 3, | ||
lymphoepithelial | |||
carcinoma | |||
| sheets/syncytial, vescicular nuclei, prominent nucleoli, pink cytoplasm | | sheets/syncytial, vescicular nuclei, prominent nucleoli, pink cytoplasm | ||
| | |<nowiki>+ve</nowiki> | ||
| most common | | most common | ||
| | | | ||
|- | |- | ||
| | | Basaloid squamous cell carcinoma (BSCC) | ||
| | | | ||
| mimics basal cell carcinoma | | mimics basal cell carcinoma | ||
| | | | ||
Revision as of 16:09, 19 February 2019
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Nasopharyngeal carcinoma Microchapters |
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Differentiating Nasopharyngeal carcinoma from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Nasopharyngeal carcinoma classification On the Web |
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American Roentgen Ray Society Images of Nasopharyngeal carcinoma classification |
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Risk calculators and risk factors for Nasopharyngeal carcinoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Homa Najafi, M.D.[2]Faizan Sheraz, M.D. [3]
Overview
Nasopharyngeal carcinoma may be classified according to microscopic features into 3 subtypes: keratinizing squamous cell carcinoma, nonkeratinizing carcinoma, and undifferentiated type.
Classification
Histologic classification
World Health Classification (2005) for NPC
| Classification | Former name | Description | EBV | Prevalence | Prognosis |
|---|---|---|---|---|---|
| Keratinizing | Type 1, squamous cell
carcinoma |
graded poorly-well-differentiated | -ve | poor | |
| Nonkeratinizing, differentiated | Type 2, transitional
carcinoma |
well defined cell borders & tumor nest borders | +ve | good | |
| Nonkeratinizing, undifferentiated | Type 3,
lymphoepithelial carcinoma |
sheets/syncytial, vescicular nuclei, prominent nucleoli, pink cytoplasm | +ve | most common | |
| Basaloid squamous cell carcinoma (BSCC) | mimics basal cell carcinoma | least common |