NUPL2: Difference between revisions

Jump to navigation Jump to search
m (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}))
 
m (Bot: HTTP→HTTPS)
 
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Nucleoporin-like 2''' is a [[protein]] that in [[human]]s is encoded by the ''NUPL2'' [[gene]].<ref name="pmid10358091">{{cite journal |vauthors=Farjot G, Sergeant A, Mikaelian I | title = A new nucleoporin-like protein interacts with both HIV-1 Rev nuclear export signal and CRM-1 | journal = J Biol Chem | volume = 274 | issue = 24 | pages = 17309–17317 |date=Jul 1999 | pmid = 10358091 | pmc = | doi =10.1074/jbc.274.24.17309  }}</ref><ref name="pmid9450185">{{cite journal |vauthors=Van Laer L, Van Camp G, van Zuijlen D, Green ED, Verstreken M, Schatteman I, Van de Heyning P, Balemans W, Coucke P, Greinwald JH, Smith RJ, Huizing E, Willems P | title = Refined mapping of a gene for autosomal dominant progressive sensorineural hearing loss (DFNA5) to a 2-cM region, and exclusion of a candidate gene that is expressed in the cochlea | journal = Eur J Hum Genet | volume = 5 | issue = 6 | pages = 397–405 |date=Mar 1998 | pmid = 9450185 | pmc =  | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: NUPL2 nucleoporin like 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11097| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Nucleoporin like 2
| HGNCid = 17010
| Symbol = NUPL2
| AltSymbols =; CG1; NLP-1; NLP_1; hCG1
| OMIM = 
| ECnumber = 
| Homologene = 40573
| MGIid = 2387631
| GeneAtlas_image1 = PBB_GE_NUPL2_204003_s_at_tn.png
| Function = {{GNF_GO|id=GO:0003676 |text = nucleic acid binding}} {{GNF_GO|id=GO:0005049 |text = nuclear export signal receptor activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005643 |text = nuclear pore}}  
| Process = {{GNF_GO|id=GO:0006611 |text = protein export from nucleus}} {{GNF_GO|id=GO:0015031 |text = protein transport}} {{GNF_GO|id=GO:0051028 |text = mRNA transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 11097
    | Hs_Ensembl = ENSG00000136243
    | Hs_RefseqProtein = NP_031368
    | Hs_RefseqmRNA = NM_007342
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 7
    | Hs_GenLoc_start = 23188011
    | Hs_GenLoc_end = 23207149
    | Hs_Uniprot = O15504
    | Mm_EntrezGene = 231042
    | Mm_Ensembl = ENSMUSG00000048439
    | Mm_RefseqmRNA = NM_153092
    | Mm_RefseqProtein = NP_694732
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 5
    | Mm_GenLoc_start = 23675028
    | Mm_GenLoc_end = 23694073
    | Mm_Uniprot = Q8CIC2
  }}
}}
'''Nucleoporin like 2''', also known as '''NUPL2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: NUPL2 nucleoporin like 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11097| accessdate = }}</ref>
 
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
{{PBB_Summary
Line 55: Line 8:


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Van Laer L, Van Camp G, van Zuijlen D, ''et al.'' |title=Refined mapping of a gene for autosomal dominant progressive sensorineural hearing loss (DFNA5) to a 2-cM region, and exclusion of a candidate gene that is expressed in the cochlea. |journal=Eur. J. Hum. Genet. |volume=5 |issue= 6 |pages= 397-405 |year= 1998 |pmid= 9450185 |doi=  }}
*{{cite journal  | author=Fouchier RA |title=Interaction of the human immunodeficiency virus type 1 Vpr protein with the nuclear pore complex |journal=J. Virol. |volume=72 |issue= 7 |pages= 6004–13 |year= 1998 |pmid= 9621063 |doi=  | pmc=110405 |name-list-format=vanc| author2=Meyer BE | author3=Simon JH | display-authors=3  | last4=Fischer  | first4=| last5=Albright  | first5=AV  | last6=González-Scarano  | first6=| last7=Malim  | first7=MH }}
*{{cite journal | author=Fouchier RA, Meyer BE, Simon JH, ''et al.'' |title=Interaction of the human immunodeficiency virus type 1 Vpr protein with the nuclear pore complex. |journal=J. Virol. |volume=72 |issue= 7 |pages= 6004-13 |year= 1998 |pmid= 9621063 |doi=  }}
*{{cite journal  | author=Katahira J |title=The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human |journal=EMBO J. |volume=18 |issue= 9 |pages= 2593–2609 |year= 1999 |pmid= 10228171 |doi= 10.1093/emboj/18.9.2593  | pmc=1171339  |name-list-format=vanc| author2=Strässer K  | author3=Podtelejnikov A  | display-authors=| last4=Mann  | first4=Matthias  | last5=Jung  | first5=Jae U.  | last6=Hurt | first6=Ed }}
*{{cite journal  | author=Katahira J, Strässer K, Podtelejnikov A, ''et al.'' |title=The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human. |journal=EMBO J. |volume=18 |issue= 9 |pages= 2593-609 |year= 1999 |pmid= 10228171 |doi= 10.1093/emboj/18.9.2593 }}
*{{cite journal  | author=Strahm Y |title=The RNA export factor Gle1p is located on the cytoplasmic fibrils of the NPC and physically interacts with the FG-nucleoporin Rip1p, the DEAD-box protein Rat8p/Dbp5p and a new protein Ymr 255p |journal=EMBO J. |volume=18 |issue= 20 |pages= 5761–5777 |year= 1999 |pmid= 10610322 |doi= 10.1093/emboj/18.20.5761 | pmc=1171643  |name-list-format=vanc| author2=Fahrenkrog B  | author3=Zenklusen D  | display-authors=3  | last4=Rychner  | first4=E  | last5=Kantor  | first5=J  | last6=Rosbach  | first6=M  | last7=Stutz  | first7=F }}
*{{cite journal | author=Farjot G, Sergeant A, Mikaélian I |title=A new nucleoporin-like protein interacts with both HIV-1 Rev nuclear export signal and CRM-1. |journal=J. Biol. Chem. |volume=274 |issue= 24 |pages= 17309-17 |year= 1999 |pmid= 10358091 |doi=  }}
*{{cite journal  | author=de Noronha CM |title=Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr |journal=Science |volume=294 |issue= 5544 |pages= 1105–1108 |year= 2001 |pmid= 11691994 |doi= 10.1126/science.1063957 |name-list-format=vanc| author2=Sherman MP  | author3=Lin HW  | display-authors=3  | last4=Cavrois  | first4=MV  | last5=Moir  | first5=RD  | last6=Goldman  | first6=RD  | last7=Greene  | first7=WC }}
*{{cite journal  | author=Strahm Y, Fahrenkrog B, Zenklusen D, ''et al.'' |title=The RNA export factor Gle1p is located on the cytoplasmic fibrils of the NPC and physically interacts with the FG-nucleoporin Rip1p, the DEAD-box protein Rat8p/Dbp5p and a new protein Ymr 255p. |journal=EMBO J. |volume=18 |issue= 20 |pages= 5761-77 |year= 1999 |pmid= 10610322 |doi= 10.1093/emboj/18.20.5761 }}
*{{cite journal  | author=Le Rouzic E |title=Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1 |journal=J. Biol. Chem. |volume=277 |issue= 47 |pages= 45091–45098 |year= 2003 |pmid= 12228227 |doi= 10.1074/jbc.M207439200 |name-list-format=vanc| author2=Mousnier A  | author3=Rustum C  | display-authors=3  | last4=Stutz  | first4=F  | last5=Hallberg  | first5=E  | last6=Dargemont  | first6=C  | last7=Benichou  | first7=S }}
*{{cite journal  | author=de Noronha CM, Sherman MP, Lin HW, ''et al.'' |title=Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr. |journal=Science |volume=294 |issue= 5544 |pages= 1105-8 |year= 2001 |pmid= 11691994 |doi= 10.1126/science.1063957 }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–16903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Le Rouzic E, Mousnier A, Rustum C, ''et al.'' |title=Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1. |journal=J. Biol. Chem. |volume=277 |issue= 47 |pages= 45091-8 |year= 2003 |pmid= 12228227 |doi= 10.1074/jbc.M207439200 }}
*{{cite journal  | author=Scherer SW |title=Human chromosome 7: DNA sequence and biology |journal=Science |volume=300 |issue= 5620 |pages= 767–772 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 | pmc=2882961  |name-list-format=vanc| author2=Cheung J  | author3=MacDonald JR  | display-authors=3  | last4=Osborne  | first4=LR  | last5=Nakabayashi  | first5=K  | last6=Herbrick  | first6=JA  | last7=Carson  | first7=AR  | last8=Parker-Katiraee  | first8=L  | last9=Skaug  | first9=J }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Gerhard DS |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–2127 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal  | author=Scherer SW, Cheung J, MacDonald JR, ''et al.'' |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767-72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 }}
*{{cite journal  | author=Sasaki M |title=Molecular cloning and functional characterization of mouse Nxf family gene products |journal=Genomics |volume=85 |issue= 5 |pages= 641–653 |year= 2005 |pmid= 15820316 |doi= 10.1016/j.ygeno.2005.01.003 |name-list-format=vanc| author2=Takeda E  | author3=Takano K  | display-authors=3  | last4=Yomogida  | first4=Kentarou  | last5=Katahira  | first5=Jun  | last6=Yoneda  | first6=Yoshihiro }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Kendirgi F |title=Interaction between the shuttling mRNA export factor Gle1 and the nucleoporin hCG1: a conserved mechanism in the export of Hsp70 mRNA |journal=Mol. Biol. Cell |volume=16 |issue= 9 |pages= 4304–4315 |year= 2006 |pmid= 16000379 |doi= 10.1091/mbc.E04-11-0998 | pmc=1196339  |name-list-format=vanc| author2=Rexer DJ  | author3=Alcázar-Román AR  | display-authors=3  | last4=Onishko  | first4=HM  | last5=Wente  | first5=SR }}
*{{cite journal  | author=Sasaki M, Takeda E, Takano K, ''et al.'' |title=Molecular cloning and functional characterization of mouse Nxf family gene products. |journal=Genomics |volume=85 |issue= 5 |pages= 641-53 |year= 2005 |pmid= 15820316 |doi= 10.1016/j.ygeno.2005.01.003 }}
*{{cite journal  |vauthors=Deniaud A, Brenner C, Kroemer G |title=Mitochondrial membrane permeabilization by HIV-1 Vpr |journal=Mitochondrion |volume=4 |issue= 2–3 |pages= 223–233 |year= 2005 |pmid= 16120388 |doi= 10.1016/j.mito.2004.06.012 }}
*{{cite journal  | author=Kendirgi F, Rexer DJ, Alcázar-Román AR, ''et al.'' |title=Interaction between the shuttling mRNA export factor Gle1 and the nucleoporin hCG1: a conserved mechanism in the export of Hsp70 mRNA. |journal=Mol. Biol. Cell |volume=16 |issue= 9 |pages= 4304-15 |year= 2006 |pmid= 16000379 |doi= 10.1091/mbc.E04-11-0998 }}
*{{cite journal  | author=Deniaud A, Brenner C, Kroemer G |title=Mitochondrial membrane permeabilization by HIV-1 Vpr. |journal=Mitochondrion |volume=4 |issue= 2-3 |pages= 223-33 |year= 2005 |pmid= 16120388 |doi= 10.1016/j.mito.2004.06.012 }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{WikiDoc Sources}}
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
 
{{gene-7-stub}}

Latest revision as of 13:21, 5 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Nucleoporin-like 2 is a protein that in humans is encoded by the NUPL2 gene.[1][2][3]


References

  1. Farjot G, Sergeant A, Mikaelian I (Jul 1999). "A new nucleoporin-like protein interacts with both HIV-1 Rev nuclear export signal and CRM-1". J Biol Chem. 274 (24): 17309–17317. doi:10.1074/jbc.274.24.17309. PMID 10358091.
  2. Van Laer L, Van Camp G, van Zuijlen D, Green ED, Verstreken M, Schatteman I, Van de Heyning P, Balemans W, Coucke P, Greinwald JH, Smith RJ, Huizing E, Willems P (Mar 1998). "Refined mapping of a gene for autosomal dominant progressive sensorineural hearing loss (DFNA5) to a 2-cM region, and exclusion of a candidate gene that is expressed in the cochlea". Eur J Hum Genet. 5 (6): 397–405. PMID 9450185.
  3. "Entrez Gene: NUPL2 nucleoporin like 2".

Further reading