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{{Infobox_gene}}
{{PBB_Controls
'''Nuclear distribution protein nudE-like 1''' is a [[protein]] that in humans is encoded by the ''NDEL1'' [[gene]].<ref name="pmid11163260">{{cite journal | vauthors = Niethammer M, Smith DS, Ayala R, Peng J, Ko J, Lee MS, Morabito M, Tsai LH | title = NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein | journal = Neuron | volume = 28 | issue = 3 | pages = 697–711 | date = Dec 2000 | pmid = 11163260 | pmc =  | doi = 10.1016/S0896-6273(00)00147-1 }}</ref><ref name="pmid11163259">{{cite journal | vauthors = Sasaki S, Shionoya A, Ishida M, Gambello MJ, Yingling J, Wynshaw-Boris A, Hirotsune S | title = A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system | journal = Neuron | volume = 28 | issue = 3 | pages = 681–96 | date = Dec 2000 | pmid = 11163259 | pmc =  | doi = 10.1016/S0896-6273(00)00146-X }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: NDEL1 nudE nuclear distribution gene E homolog (A. nidulans)-like 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81565| accessdate = }}</ref>
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| update_protein_box = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
This gene encodes a [[thiol]]-activated [[oligopeptidase]] that is phosphorylated in [[M phase]] of the [[cell cycle]]. [[Phosphorylation]] regulates the cell cycle-dependent distribution of this [[protein]], with a fraction of the protein bound strongly to [[centrosome]]s in [[interphase]] and localized to [[mitotic spindle]]s in early M phase. Overall, this protein plays a role in [[nervous system]] development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.<ref name="entrez"/>
{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = NudE nuclear distribution gene E homolog (A. nidulans)-like 1
| HGNCid = 17620
| Symbol = NDEL1
| AltSymbols =; DKFZp451M0318; EOPA; MITAP1; NUDEL
| OMIM = 607538
| ECnumber = 
| Homologene = 32567
| MGIid = 1932915
| GeneAtlas_image1 = PBB_GE_NDEL1_208093_s_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005856 |text = cytoskeleton}} {{GNF_GO|id=GO:0005874 |text = microtubule}}
| Process = {{GNF_GO|id=GO:0006810 |text = transport}} {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0007399 |text = nervous system development}} {{GNF_GO|id=GO:0030154 |text = cell differentiation}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 81565
    | Hs_Ensembl = ENSG00000166579
    | Hs_RefseqProtein = NP_001020750
    | Hs_RefseqmRNA = NM_001025579
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 17
    | Hs_GenLoc_start = 8279895
    | Hs_GenLoc_end = 8324667
    | Hs_Uniprot = Q9GZM8
    | Mm_EntrezGene = 83431
    | Mm_Ensembl = ENSMUSG00000018736
    | Mm_RefseqmRNA = NM_023668
    | Mm_RefseqProtein = NP_076157
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 68637629
    | Mm_GenLoc_end = 68688055
    | Mm_Uniprot = Q9ERR1
  }}
}}
'''NudE nuclear distribution gene E homolog (A. nidulans)-like 1''', also known as '''NDEL1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: NDEL1 nudE nuclear distribution gene E homolog (A. nidulans)-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81565| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{PBB_Summary
| section_title =  
| summary_text = This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.<ref name="entrez">{{cite web | title = Entrez Gene: NDEL1 nudE nuclear distribution gene E homolog (A. nidulans)-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81565| accessdate = }}</ref>
}}


==References==
NDEL1 has been shown to [[Protein-protein interaction|interact]] with [[Cyclin-dependent kinase 5]],<ref name=pmid11163260 /> [[YWHAE]],<ref name=pmid12796778>{{cite journal | vauthors = Toyo-oka K, Shionoya A, Gambello MJ, Cardoso C, Leventer R, Ward HL, Ayala R, Tsai LH, Dobyns W, Ledbetter D, Hirotsune S, Wynshaw-Boris A | title = 14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome | journal = Nature Genetics | volume = 34 | issue = 3 | pages = 274–85 | date = Jul 2003 | pmid = 12796778 | doi = 10.1038/ng1169 }}</ref> [[PAFAH1B1]]<ref name=pmid11163260/><ref name=pmid12796778/> and [[DISC1]].<ref name=pmid12812986>{{cite journal | vauthors = Morris JA, Kandpal G, Ma L, Austin CP | title = DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation | journal = Human Molecular Genetics | volume = 12 | issue = 13 | pages = 1591–608 | date = Jul 2003 | pmid = 12812986 | doi = 10.1093/hmg/ddg162 }}</ref><ref name=pmid12506198>{{cite journal | vauthors = Ozeki Y, Tomoda T, Kleiderlein J, Kamiya A, Bord L, Fujii K, Okawa M, Yamada N, Hatten ME, Snyder SH, Ross CA, Sawa A | title = Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 100 | issue = 1 | pages = 289–94 | date = Jan 2003 | pmid = 12506198 | pmc = 140954 | doi = 10.1073/pnas.0136913100 }}</ref>
{{reflist|2}}
 
==Further reading==
== References ==
{{reflist}}
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA | title = A "double adaptor" method for improved shotgun library construction | journal = Analytical Biochemistry | volume = 236 | issue = 1 | pages = 107–13 | date = Apr 1996 | pmid = 8619474 | doi = 10.1006/abio.1996.0138 }}
| citations =
* {{cite journal | vauthors = Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA | title = Large-scale concatenation cDNA sequencing | journal = Genome Research | volume = 7 | issue = 4 | pages = 353–8 | date = Apr 1997 | pmid = 9110174 | pmc = 139146 | doi = 10.1101/gr.7.4.353 }}
*{{cite journal | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
* {{cite journal | vauthors = Dias Neto E, Correa RG, Verjovski-Almeida S, Briones MR, Nagai MA, da Silva W, Zago MA, Bordin S, Costa FF, Goldman GH, Carvalho AF, Matsukuma A, Baia GS, Simpson DH, Brunstein A, de Oliveira PS, Bucher P, Jongeneel CV, O'Hare MJ, Soares F, Brentani RR, Reis LF, de Souza SJ, Simpson AJ | title = Shotgun sequencing of the human transcriptome with ORF expressed sequence tags | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 7 | pages = 3491–6 | date = Mar 2000 | pmid = 10737800 | pmc = 16267 | doi = 10.1073/pnas.97.7.3491 }}
*{{cite journal | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi= }}
* {{cite journal | vauthors = Feng Y, Olson EC, Stukenberg PT, Flanagan LA, Kirschner MW, Walsh CA | title = LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome | journal = Neuron | volume = 28 | issue = 3 | pages = 665–79 | date = Dec 2000 | pmid = 11163258 | doi = 10.1016/S0896-6273(00)00145-8 }}
*{{cite journal | author=Dias Neto E, Correa RG, Verjovski-Almeida S, ''et al.'' |title=Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 7 |pages= 3491-6 |year= 2000 |pmid= 10737800 |doi= }}
* {{cite journal | vauthors = Ozeki Y, Tomoda T, Kleiderlein J, Kamiya A, Bord L, Fujii K, Okawa M, Yamada N, Hatten ME, Snyder SH, Ross CA, Sawa A | title = Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 100 | issue = 1 | pages = 289–94 | date = Jan 2003 | pmid = 12506198 | pmc = 140954 | doi = 10.1073/pnas.0136913100 }}
*{{cite journal  | author=Feng Y, Olson EC, Stukenberg PT, ''et al.'' |title=LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome. |journal=Neuron |volume=28 |issue= 3 |pages= 665-79 |year= 2001 |pmid= 11163258 |doi= }}
* {{cite journal | vauthors = Yan X, Li F, Liang Y, Shen Y, Zhao X, Huang Q, Zhu X | title = Human Nudel and NudE as regulators of cytoplasmic dynein in poleward protein transport along the mitotic spindle | journal = Molecular and Cellular Biology | volume = 23 | issue = 4 | pages = 1239–50 | date = Feb 2003 | pmid = 12556484 | pmc = 141156 | doi = 10.1128/MCB.23.4.1239-1250.2003 }}
*{{cite journal | author=Sasaki S, Shionoya A, Ishida M, ''et al.'' |title=A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system. |journal=Neuron |volume=28 |issue= 3 |pages= 681-96 |year= 2001 |pmid= 11163259 |doi= }}
* {{cite journal | vauthors = Cardoso C, Leventer RJ, Ward HL, Toyo-Oka K, Chung J, Gross A, Martin CL, Allanson J, Pilz DT, Olney AH, Mutchinick OM, Hirotsune S, Wynshaw-Boris A, Dobyns WB, Ledbetter DH | title = Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3 | journal = American Journal of Human Genetics | volume = 72 | issue = 4 | pages = 918–30 | date = Apr 2003 | pmid = 12621583 | pmc = 1180354 | doi = 10.1086/374320 }}
*{{cite journal | author=Niethammer M, Smith DS, Ayala R, ''et al.'' |title=NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. |journal=Neuron |volume=28 |issue= 3 |pages= 697-711 |year= 2001 |pmid= 11163260 |doi= }}
* {{cite journal | vauthors = Toyo-oka K, Shionoya A, Gambello MJ, Cardoso C, Leventer R, Ward HL, Ayala R, Tsai LH, Dobyns W, Ledbetter D, Hirotsune S, Wynshaw-Boris A | title = 14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome | journal = Nature Genetics | volume = 34 | issue = 3 | pages = 274–85 | date = Jul 2003 | pmid = 12796778 | doi = 10.1038/ng1169 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Morris JA, Kandpal G, Ma L, Austin CP | title = DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation | journal = Human Molecular Genetics | volume = 12 | issue = 13 | pages = 1591–608 | date = Jul 2003 | pmid = 12812986 | doi = 10.1093/hmg/ddg162 }}
*{{cite journal | author=Ozeki Y, Tomoda T, Kleiderlein J, ''et al.'' |title=Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 1 |pages= 289-94 |year= 2003 |pmid= 12506198 |doi= 10.1073/pnas.0136913100 }}
* {{cite journal | vauthors = Brandon NJ, Handford EJ, Schurov I, Rain JC, Pelling M, Duran-Jimeniz B, Camargo LM, Oliver KR, Beher D, Shearman MS, Whiting PJ | title = Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders | journal = Molecular and Cellular Neurosciences | volume = 25 | issue = 1 | pages = 42–55 | date = Jan 2004 | pmid = 14962739 | doi = 10.1016/j.mcn.2003.09.009 }}
*{{cite journal | author=Yan X, Li F, Liang Y, ''et al.'' |title=Human Nudel and NudE as regulators of cytoplasmic dynein in poleward protein transport along the mitotic spindle. |journal=Mol. Cell. Biol. |volume=23 |issue= 4 |pages= 1239-50 |year= 2003 |pmid= 12556484 |doi= }}
* {{cite journal | vauthors = Liang Y, Yu W, Li Y, Yang Z, Yan X, Huang Q, Zhu X | title = Nudel functions in membrane traffic mainly through association with Lis1 and cytoplasmic dynein | journal = The Journal of Cell Biology | volume = 164 | issue = 4 | pages = 557–66 | date = Feb 2004 | pmid = 14970193 | pmc = 2171987 | doi = 10.1083/jcb.200308058 }}
*{{cite journal | author=Cardoso C, Leventer RJ, Ward HL, ''et al.'' |title=Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3. |journal=Am. J. Hum. Genet. |volume=72 |issue= 4 |pages= 918-30 |year= 2003 |pmid= 12621583 |doi= }}
* {{cite journal | vauthors = Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S | title = Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions | journal = Genome Research | volume = 14 | issue = 9 | pages = 1711–8 | date = Sep 2004 | pmid = 15342556 | pmc = 515316 | doi = 10.1101/gr.2435604 }}
*{{cite journal | author=Toyo-oka K, Shionoya A, Gambello MJ, ''et al.'' |title=14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. |journal=Nat. Genet. |volume=34 |issue= 3 |pages= 274-85 |year= 2003 |pmid= 12796778 |doi= 10.1038/ng1169 }}
* {{cite journal | vauthors = Tarricone C, Perrina F, Monzani S, Massimiliano L, Kim MH, Derewenda ZS, Knapp S, Tsai LH, Musacchio A | title = Coupling PAF signaling to dynein regulation: structure of LIS1 in complex with PAF-acetylhydrolase | journal = Neuron | volume = 44 | issue = 5 | pages = 809–21 | date = Dec 2004 | pmid = 15572112 | doi = 10.1016/j.neuron.2004.11.019 }}
*{{cite journal | author=Morris JA, Kandpal G, Ma L, Austin CP |title=DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation. |journal=Hum. Mol. Genet. |volume=12 |issue= 13 |pages= 1591-608 |year= 2004 |pmid= 12812986 |doi= }}
* {{cite journal | vauthors = Hayashi MA, Portaro FC, Bastos MF, Guerreiro JR, Oliveira V, Gorrão SS, Tambourgi DV, Sant'Anna OA, Whiting PJ, Camargo LM, Konno K, Brandon NJ, Camargo AC | title = Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1 | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 102 | issue = 10 | pages = 3828–33 | date = Mar 2005 | pmid = 15728732 | pmc = 553309 | doi = 10.1073/pnas.0500330102 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
* {{cite journal | vauthors = Guerreiro JR, Winnischofer SM, Bastos MF, Portaro FC, Sogayar MC, de Camargo AC, Hayashi MA | title = Cloning and characterization of the human and rabbit NUDEL-oligopeptidase promoters and their negative regulation | journal = Biochimica et Biophysica Acta | volume = 1730 | issue = 1 | pages = 77–84 | date = Jul 2005 | pmid = 16005531 | doi = 10.1016/j.bbaexp.2005.06.001 }}
*{{cite journal | author=Brandon NJ, Handford EJ, Schurov I, ''et al.'' |title=Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders. |journal=Mol. Cell. Neurosci. |volume=25 |issue= 1 |pages= 42-55 |year= 2004 |pmid= 14962739 |doi= 10.1016/j.mcn.2003.09.009 }}
*{{cite journal | author=Liang Y, Yu W, Li Y, ''et al.'' |title=Nudel functions in membrane traffic mainly through association with Lis1 and cytoplasmic dynein. |journal=J. Cell Biol. |volume=164 |issue= 4 |pages= 557-66 |year= 2004 |pmid= 14970193 |doi= 10.1083/jcb.200308058 }}
*{{cite journal  | author=Suzuki Y, Yamashita R, Shirota M, ''et al.'' |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711-8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Tarricone C, Perrina F, Monzani S, ''et al.'' |title=Coupling PAF signaling to dynein regulation: structure of LIS1 in complex with PAF-acetylhydrolase. |journal=Neuron |volume=44 |issue= 5 |pages= 809-21 |year= 2005 |pmid= 15572112 |doi= 10.1016/j.neuron.2004.11.019 }}
*{{cite journal  | author=Hayashi MA, Portaro FC, Bastos MF, ''et al.'' |title=Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 10 |pages= 3828-33 |year= 2005 |pmid= 15728732 |doi= 10.1073/pnas.0500330102 }}
*{{cite journal | author=Guerreiro JR, Winnischofer SM, Bastos MF, ''et al.'' |title=Cloning and characterization of the human and rabbit NUDEL-oligopeptidase promoters and their negative regulation. |journal=Biochim. Biophys. Acta |volume=1730 |issue= 1 |pages= 77-84 |year= 2005 |pmid= 16005531 |doi= 10.1016/j.bbaexp.2005.06.001 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
[[Category:Human proteins]]
{{WikiDoc Sources}}
 
 
{{gene-17-stub}}

Latest revision as of 12:43, 5 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Nuclear distribution protein nudE-like 1 is a protein that in humans is encoded by the NDEL1 gene.[1][2][3]

This gene encodes a thiol-activated oligopeptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[3]

Interactions

NDEL1 has been shown to interact with Cyclin-dependent kinase 5,[1] YWHAE,[4] PAFAH1B1[1][4] and DISC1.[5][6]

References

  1. ↑ 1.0 1.1 1.2 Niethammer M, Smith DS, Ayala R, Peng J, Ko J, Lee MS, Morabito M, Tsai LH (Dec 2000). "NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein". Neuron. 28 (3): 697–711. doi:10.1016/S0896-6273(00)00147-1. PMID 11163260.
  2. ↑ Sasaki S, Shionoya A, Ishida M, Gambello MJ, Yingling J, Wynshaw-Boris A, Hirotsune S (Dec 2000). "A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system". Neuron. 28 (3): 681–96. doi:10.1016/S0896-6273(00)00146-X. PMID 11163259.
  3. ↑ 3.0 3.1 "Entrez Gene: NDEL1 nudE nuclear distribution gene E homolog (A. nidulans)-like 1".
  4. ↑ 4.0 4.1 Toyo-oka K, Shionoya A, Gambello MJ, Cardoso C, Leventer R, Ward HL, Ayala R, Tsai LH, Dobyns W, Ledbetter D, Hirotsune S, Wynshaw-Boris A (Jul 2003). "14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome". Nature Genetics. 34 (3): 274–85. doi:10.1038/ng1169. PMID 12796778.
  5. ↑ Morris JA, Kandpal G, Ma L, Austin CP (Jul 2003). "DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation". Human Molecular Genetics. 12 (13): 1591–608. doi:10.1093/hmg/ddg162. PMID 12812986.
  6. ↑ Ozeki Y, Tomoda T, Kleiderlein J, Kamiya A, Bord L, Fujii K, Okawa M, Yamada N, Hatten ME, Snyder SH, Ross CA, Sawa A (Jan 2003). "Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth". Proceedings of the National Academy of Sciences of the United States of America. 100 (1): 289–94. doi:10.1073/pnas.0136913100. PMC 140954. PMID 12506198.

Further reading


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