Mycosis fungoides classification: Difference between revisions

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:* Blastic NK-cell lymphoma
:* Blastic NK-cell lymphoma


Based on the organ involvement, cutaneous T cell lymphoma may be classified into:<ref name= canadiancancer> Cutaneous T cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/cutaneous-t-cell-lymphoma/?region=on Accessed on January 19, 2016</ref>
Based on the organ involvement, cutaneous T cell lymphoma may be classified into:<ref name="canadiancancer">Cutaneous T cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/cutaneous-t-cell-lymphoma/?region=on Accessed on January 19, 2016</ref>
* [[Mycosis fungoides]] (MF)  
* [[Mycosis fungoides]] (MF)  
* [[Sézary syndrome]] (SS)   
* [[Sézary syndrome]] (SS)   


{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
{| style="border: 0px; font-size: 90%; margin: 3px;" align="center"
|+ '''Cutaneous T cell lymphoma classification<ref name= canadiancancer> Cutaneous T cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/cutaneous-t-cell-lymphoma/?region=on Accessed on January 19, 2016</ref>'''
|+ '''Cutaneous T cell lymphoma classification<ref name="canadiancancer">Cutaneous T cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/cutaneous-t-cell-lymphoma/?region=on Accessed on January 19, 2016</ref>'''
! style="background: #4479BA;; color:#FFF;" | Name
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! style="background: #4479BA;; color:#FFF;" | Description
! style="background: #4479BA;; color:#FFF;" | Description
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* Most common form of cutaneous T cell lymphoma
* Most common form of cutaneous T cell lymphoma
* Starts in the skin in areas of the body not usually exposed to the sun
* Starts in the skin in areas of the body not usually exposed to the sun
* May appear as a scaly, pink or red rash or patches on the skin
* May appear as a scaly, pink patches on the skin
* Signs can progress to skin tumours in more advanced cases
* Signs can progress to the development of skin tumors in more advanced cases
|-
|-
| style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | '''Sézary syndrome'''  (SS)   
| style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | '''Sézary syndrome'''  (SS)   
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* Affects skin, blood, and lymph nodes
* Affects skin, blood, and lymph nodes
:* Large areas of the skin are affected  
:* Large areas of the skin are affected  
:* Skin is often red, itchy, painful and peeling
:* Skin is often red, itchy, painful, and peeling
:* Skin tumours can also appear
:* Skin tumors can also appear
:* Entire body can be affected, also known as "red man syndrome"
:* Entire body can be affected, also known as "red man syndrome"
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{| style="border: 0px; font-size: 90%; margin: 3px;" align="center"
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
|+ '''Cutaneous T cell lymphoma classification<ref name="seer.cancer">Cutaneous T cell lymphoma. Surveillance, Epidemiology, and End Results . http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd52f7/ Accessed on January 19, 2016</ref>'''
|+ '''Cutaneous T cell lymphoma classification<ref name= seer.cancer> Cutaneous T cell lymphoma. Surveillance, Epidemiology, and End Results . http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd52f7/ Accessed on January 19, 2016</ref>'''
! style="background: #4479BA;; color:#FFF;" | Name
! style="background: #4479BA;; color:#FFF;" | Name
! style="background: #4479BA;; color:#FFF;" | Description
! style="background: #4479BA;; color:#FFF;" | Description
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* Characterized by localized or disseminated eruptive papules, nodules with tumors showing central ulceration, and necrosis or by superficial hyperkeratotic patches and plaques
* Characterized by localized or disseminated eruptive papules, nodules with tumors showing central ulceration, and necrosis or by superficial hyperkeratotic patches and plaques
* Dissemination to other visceral sites (lung, testis, CNS, and oral mucosa) possible
* Dissemination to other visceral sites (lung, testis, CNS, and oral mucosa)
* Lymph nodes seldom affected
* Lymph nodes are seldom affected
* Aggressive clinical course with median survival of 32 months
* Aggressive clinical course with median survival rate of 32 months


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* Clinical presentation is usually a solitary plaque or nodule, commonly on the face, neck, or upper trunk
* Clinical presentation is usually a solitary plaque or nodule, commonly on the face, neck, or upper trunk
* Involvement of lower extremities is rare  
* The involvement of lower extremities is rare  
* There should be an absence of patches
* Cutaneous patches are generally absent
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==References==
==References==

Revision as of 16:28, 27 January 2016

Cutaneous T cell lymphoma Microchapters

Home

Patient Information

Overview

Classification

Mycosis fungoides
Sezary syndrome

Pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

There are 3 classification methods used to classify cutaneous T cell lymphoma into several subtypes.

Classification

Cutaneous T-cell lymphomas may be classified into the following types:[1]

Based on the organ involvement, cutaneous T cell lymphoma may be classified into:[2]

Cutaneous T cell lymphoma classification[2]
Name Description
Mycosis fungoides (MF)
  • Most common form of cutaneous T cell lymphoma
  • Starts in the skin in areas of the body not usually exposed to the sun
  • May appear as a scaly, pink patches on the skin
  • Signs can progress to the development of skin tumors in more advanced cases
Sézary syndrome (SS)
  • Often the more aggressive form of cutaneous T cell lymphoma
  • An advanced form of mycosis fungoides
  • Affects skin, blood, and lymph nodes
  • Large areas of the skin are affected
  • Skin is often red, itchy, painful, and peeling
  • Skin tumors can also appear
  • Entire body can be affected, also known as "red man syndrome"
Cutaneous T cell lymphoma classification[3]
Name Description
Primary or cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma
  • Characterized by localized or disseminated eruptive papules, nodules with tumors showing central ulceration, and necrosis or by superficial hyperkeratotic patches and plaques
  • Dissemination to other visceral sites (lung, testis, CNS, and oral mucosa)
  • Lymph nodes are seldom affected
  • Aggressive clinical course with median survival rate of 32 months
Primary cutaneous CD4-positive small/medium T-cell lymphoma
  • Clinical presentation is usually a solitary plaque or nodule, commonly on the face, neck, or upper trunk
  • The involvement of lower extremities is rare
  • Cutaneous patches are generally absent

References

  1. James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  2. 2.0 2.1 Cutaneous T cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/cutaneous-t-cell-lymphoma/?region=on Accessed on January 19, 2016
  3. Cutaneous T cell lymphoma. Surveillance, Epidemiology, and End Results . http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd52f7/ Accessed on January 19, 2016


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