Mycobacterium immunogenum
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| Mycobacterium immunogenum Wilson et al. 2001,[1] ATCC 700505 |
Mycobacterium immunogenum is a species of the phylum actinobacteria (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus mycobacterium.
These non-tuberculous mycobacteria are sometimes found in fouling water-based cutting fluids, often causing hypersensitivity pneumonitis to the machinists in the affected grinding plants.[2]
Type strain
Strain BH29 = MC 779 = ATCC 700505 = CCUG 47286 = CIP 106684
Treatment
Antimicrobial regimen
- M. immunogenum isolates [3]
- susceptible: Amikacin AND Clarithromycin but
- resistant: Ciprofloxacin, Doxycycline, Cefoxitin, Tobramycin, and Sulfamethoxazole
- NOTE: The optimal therapy for this organism is unknown; however, successful therapy is likely difficult due to the extensive antibiotic resistance of the organism
References
- ↑ Wilson, RW; Steingrube, VA; Böttger, EC; Springer, B; Brown-Elliott, BA; Vincent, V; Jost Jr, KC; Zhang, Y; et al. (2001). "Mycobacterium immunogenum sp. Nov., a novel species related to Mycobacterium abscessus and associated with clinical disease, pseudo-outbreaks and contaminated metalworking fluids: an international cooperative study on mycobacterial taxonomy". International journal of systematic and evolutionary microbiology. 51 (Pt 5): 1751–64. doi:10.1099/00207713-51-5-1751. PMID 11594606.
- ↑ Wallace, R. J.; Zhang, Y.; Wilson, R. W.; Mann, L.; Rossmoore, H. (2002). "Presence of a Single Genotype of the Newly Described Species Mycobacterium immunogenum in Industrial Metalworking Fluids Associated with Hypersensitivity Pneumonitis". Applied and Environmental Microbiology. 68 (11): 5580–4. doi:10.1128/AEM.68.11.5580-5584.2002. PMC 129929. PMID 12406752.
- ↑ Griffith, David E.; Aksamit, Timothy; Brown-Elliott, Barbara A.; Catanzaro, Antonino; Daley, Charles; Gordin, Fred; Holland, Steven M.; Horsburgh, Robert; Huitt, Gwen; Iademarco, Michael F.; Iseman, Michael; Olivier, Kenneth; Ruoss, Stephen; von Reyn, C. Fordham; Wallace, Richard J.; Winthrop, Kevin; ATS Mycobacterial Diseases Subcommittee; American Thoracic Society; Infectious Disease Society of America (2007-02-15). "An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases". American Journal of Respiratory and Critical Care Medicine. 175 (4): 367–416. doi:10.1164/rccm.200604-571ST. ISSN 1073-449X. PMID 17277290.