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==Overview== | |||
The Mustard | The '''Mustard procedure''' was developed in 1963 by Dr. [[William Mustard]] at the [[Hospital for Sick Children]] in Toronto, Canada. It was the first procedure to show that [[congenital heart defect]]s could be repaired. | ||
==History== | |||
Dr. Mustard, with support from the [[Heart and Stroke Foundation of Canada]], developed the first operation to correct a congenital heart defect that produced “blue babies”. The defect is called [[transposition of the great vessels]]. The condition was common and fatal. | |||
==Pathophysiology== | |||
[[Transposition of the great vessels]] causes blood from the [[lung]]s to flow back to the lungs and blood from the body to flow back to the body. This occurs because the [[aorta]] and the [[pulmonary artery]], the two major arteries coming out of the heart, are connected to the wrong chambers. The babies look blue or [[cyanotic]] because there is insufficient oxygen circulating in their bodies.<ref name=heartandstroke>Press Release – Children who had heart surgery 20-30 years ago should keep in touch, June 6, 2001, Heart and Stroke Foundation of Canada. URL: [http://ww2.heartandstroke.ca/Page.asp?PageID=33&ArticleID=1056 http://ww2.heartandstroke.ca/Page.asp?PageID=33&ArticleID=1056]. Accessed on: January 14, 2008.</ref> | |||
==Surgical procedure== | |||
The Mustard Procedure allows total correction of transposition of the great vessels. The procedure employs a baffle to direct oxygenated pulmonary venous return into the right atrium and thence into the right ventricle which is the pumping ventricle for the aorta and the systemic circulation.<ref>Yale University School of Medicine, http://www.med.yale.edu/intmed/cardio/chd/surgery_mustard/index.html</ref> In other words, the Mustard Procedure restores the circulation but reverses the direction of the blood flow in the heart. | |||
In a normal heart, de-oxygenated, blue, blood is pumped into the lungs via the [[right ventricle]]. Then it is distributed throughout the body via the left ventricle. In the Mustard procedure, blood is pumped to the lungs via the [[left ventricle]] and disseminated throughout the body via the right ventricle.<ref name=heartandstroke/> | |||
==Efficacy of the procedure== | |||
The Mustard procedure reduced an 80% [[mortality]] in the first year of life to an 80% survival at age 20. | The Mustard procedure reduced an 80% [[mortality]] in the first year of life to an 80% survival at age 20. | ||
==See also== | ==See also== | ||
* [[Congenital heart disease]] | * [[Congenital heart disease]] | ||
The Mustard procedure was largely replaced in the late 1970s by the Jatene procedure (arterial switch), in which the native arteries were switches so that the RV would be connected to the pulmonary artery and the LV would be connected to the aorta. | The Mustard procedure was largely replaced in the late 1970s by the [[Jatene procedure]] (arterial switch), in which the native arteries were switches so that the [[RV]] would be connected to the [[pulmonary artery]] and the [[LV]] would be connected to the aorta. This surgery had not been possible prior to 1975 because of difficulty with re-implanting coronary arteries. | ||
==References== | ==References== | ||
{{reflist}} | {{reflist|2}} | ||
{{Cardiac surgery procedures}} | {{Cardiac surgery procedures}} | ||
[[Category:Cardiac surgery]] | [[Category:Cardiac surgery]] | ||
{{WH}} | |||
{{WS}} | |||
Latest revision as of 07:57, 10 August 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The Mustard procedure was developed in 1963 by Dr. William Mustard at the Hospital for Sick Children in Toronto, Canada. It was the first procedure to show that congenital heart defects could be repaired.
History
Dr. Mustard, with support from the Heart and Stroke Foundation of Canada, developed the first operation to correct a congenital heart defect that produced “blue babies”. The defect is called transposition of the great vessels. The condition was common and fatal.
Pathophysiology
Transposition of the great vessels causes blood from the lungs to flow back to the lungs and blood from the body to flow back to the body. This occurs because the aorta and the pulmonary artery, the two major arteries coming out of the heart, are connected to the wrong chambers. The babies look blue or cyanotic because there is insufficient oxygen circulating in their bodies.[1]
Surgical procedure
The Mustard Procedure allows total correction of transposition of the great vessels. The procedure employs a baffle to direct oxygenated pulmonary venous return into the right atrium and thence into the right ventricle which is the pumping ventricle for the aorta and the systemic circulation.[2] In other words, the Mustard Procedure restores the circulation but reverses the direction of the blood flow in the heart.
In a normal heart, de-oxygenated, blue, blood is pumped into the lungs via the right ventricle. Then it is distributed throughout the body via the left ventricle. In the Mustard procedure, blood is pumped to the lungs via the left ventricle and disseminated throughout the body via the right ventricle.[1]
Efficacy of the procedure
The Mustard procedure reduced an 80% mortality in the first year of life to an 80% survival at age 20.
See also
The Mustard procedure was largely replaced in the late 1970s by the Jatene procedure (arterial switch), in which the native arteries were switches so that the RV would be connected to the pulmonary artery and the LV would be connected to the aorta. This surgery had not been possible prior to 1975 because of difficulty with re-implanting coronary arteries.
References
- ↑ 1.0 1.1 Press Release – Children who had heart surgery 20-30 years ago should keep in touch, June 6, 2001, Heart and Stroke Foundation of Canada. URL: http://ww2.heartandstroke.ca/Page.asp?PageID=33&ArticleID=1056. Accessed on: January 14, 2008.
- ↑ Yale University School of Medicine, http://www.med.yale.edu/intmed/cardio/chd/surgery_mustard/index.html