Multiple myeloma other diagnostic studies: Difference between revisions

Jump to navigation Jump to search
Line 3: Line 3:
{{CMG}}
{{CMG}}
==Overview==
==Overview==
Biopsy and genetic testing can be performed to confirm multiple myeloma diagnosis.<ref>Multiple myeloma. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/diagnosis/?region=mb#blood_chem Accessed on September, 20th 2015</ref>
Biopsy and genetic testing may be helpful in the diagnosis of mulriple myeloma.<ref>Multiple myeloma. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/diagnosis/?region=mb#blood_chem Accessed on September, 20th 2015</ref>


==Bone Marrow Biopsy==
==Bone Marrow Biopsy==

Revision as of 20:22, 21 September 2015

Multiple myeloma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Multiple Myeloma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

Staging

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

Echocardiograph and Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Future or Investigational Therapies

Case Studies

Case #1

Multiple myeloma other diagnostic studies On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Multiple myeloma other diagnostic studies

All Images
X-rays
Echo and Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Multiple myeloma other diagnostic studies

CDC on Multiple myeloma other diagnostic studies

Multiple myeloma other diagnostic studies in the news

Blogs on Multiple myeloma other diagnostic studies

Directions to Hospitals Treating Multiple myeloma

Risk calculators and risk factors for Multiple myeloma other diagnostic studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Biopsy and genetic testing may be helpful in the diagnosis of mulriple myeloma.[1]

Bone Marrow Biopsy

  • Bone marrow biopsy is usually performed to estimate the percentage of bone marrow occupied by plasma cells.[2]
  • Examination of abnormal plasma in the bone marrow is the only way to confirm a diagnosis.[3]
  • The percentage of plasma cells is also used in the diagnostic criteria of multiple myeloma.[4]

Cytogenetic tests

  • Detects any chromosomal mutations occurring in multiple myeloma such as chromosome 13 deletion or chromosome 14 translocation.[5][6]
Karyotyping[7][8]
A sample of blood or liquid bone marrow (from a bone marrow aspiration) is examined under the microscope to look for changes in the chromosomes. Karyotyping can find large chromosomal changes like a missing chromosome.
Fluorescent in situ hybridization (FISH)[9][10]
FISH is a specific molecular genetic method used to identify chromosomal abnormalities and other genetic changes in cells using special DNA probes labelled with fluorescent dyes. FISH can find small chromosomal changes like a rearranged chromosome.

References

  1. Multiple myeloma. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/diagnosis/?region=mb#blood_chem Accessed on September, 20th 2015
  2. Multiple myeloma. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/diagnosis/?region=mb#blood_chem Accessed on September, 20th 2015
  3. Multiple myeloma. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/diagnosis/?region=mb#blood_chem Accessed on September, 20th 2015
  4. Multiple myeloma. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/diagnosis/?region=mb#blood_chem Accessed on September, 20th 2015
  5. Multiple myeloma. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/diagnosis/?region=mb#blood_chem Accessed on September, 20th 2015
  6. Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September 2015
  7. Multiple myeloma. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/diagnosis/?region=mb#blood_chem Accessed on September, 20th 2015
  8. Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September 2015
  9. Multiple myeloma. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/diagnosis/?region=mb#blood_chem Accessed on September, 20th 2015
  10. Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September 2015


Template:WikiDoc Sources