Multiple myeloma epidemiology and demographics: Difference between revisions

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==Overview==
==Overview==
In 2012, the incidence of multiple myeloma was approximately 6.3 per 100,000 cases with a mortality rate of 3.3 per 100,000 cases in the United States.<ref name="PCN">Plasma cell neoplasm.National cancer institute (2015)http://www.cancer.gov/types/myeloma/hp/myeloma-treatment-pdq#cit/section_1.1 Accessed on September, 20th 2015</ref> The prevalence of multiple myeloma was estimated to be 89,658 cases in 2012 in the United States.<ref name="seer">Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref><ref name="wiki">Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref> Multiple myeloma is the second most common blood cancer after [[non-Hodgkin's lymphoma]] and 14th most common cancer overall in United States.<ref name="Collins-2005">{{Cite journal  | last1 = Collins | first1 = CD. | title = Problems monitoring response in multiple myeloma. | journal = Cancer Imaging | volume = 5 Spec No A | issue =  | pages = S119-26 | month =  | year = 2005 | doi = 10.1102/1470-7330.2005.0033 | PMID = 16361127 }}</ref><ref name="seer">Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref><ref name="wiki">Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref> Males are more commonly affected with multiple myeloma than females; the male to female ratio is approximately 1.54 to 1.<ref name="wiki">Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref><ref name="radio">Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref> Multiple myeloma usually affects individuals of the African American and Native Pacific Islanders race. Asian individuals are less likely to develop multiple myeloma.<ref name="wiki">Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref> The incidence of multiple myeloma increases with age; the median age at diagnosis is between 65 to 70 years.<ref name="wiki">Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref>
In 2012, the incidence of multiple myeloma was approximately 6.3 per 100,000 cases with a mortality rate of 3.3 per 100,000 cases in the United States.<ref name="PCN">Plasma cell neoplasm.National cancer institute (2015)http://www.cancer.gov/types/myeloma/hp/myeloma-treatment-pdq#cit/section_1.1 Accessed on September, 20th 2015</ref> The prevalence of multiple myeloma was estimated to be 89,658 cases in 2012 in the United States.<ref name="seer">Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref><ref name="wiki">Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref> Multiple myeloma is the second most common blood cancer after [[non-Hodgkin's lymphoma]] and 14th most common cancer overall in United States.<ref name="Collins-2005">{{Cite journal  | last1 = Collins | first1 = CD. | title = Problems monitoring response in multiple myeloma. | journal = Cancer Imaging | volume = 5 Spec No A | issue =  | pages = S119-26 | month =  | year = 2005 | doi = 10.1102/1470-7330.2005.0033 | PMID = 16361127 }}</ref><ref name="seer">Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref><ref name="wiki">Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref> Males are more commonly affected with multiple myeloma than females; the male to female ratio is approximately 1.54 to 1.<ref name="wiki">Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref><ref name="radio">Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref> Multiple myeloma usually affects individuals of the African American and Native Pacific Islanders race. Asian individuals are less likely to develop multiple myeloma.<ref name="wiki">Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref> The incidence of multiple myeloma increases with age; the median age at diagnosis is approximately 66–70 years with 37% of patients being younger than 65 years of age.PMID: 28061985


==Epidemiology and Demographics==
==Epidemiology and Demographics==
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===Race===
===Race===
*Among African Americans, multiple myeloma is one of the top 10 leading causes of cancer deaths.<ref name="seer">Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref>
*Among African Americans, multiple myeloma is one of the top 10 leading causes of cancer deaths.<ref name="seer">Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref>
*The incidence of multiple myeloma in the African American population is more than the European American population. PMID: 28061985


==Gallery==
==Gallery==

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

In 2012, the incidence of multiple myeloma was approximately 6.3 per 100,000 cases with a mortality rate of 3.3 per 100,000 cases in the United States.[1] The prevalence of multiple myeloma was estimated to be 89,658 cases in 2012 in the United States.[2][3] Multiple myeloma is the second most common blood cancer after non-Hodgkin's lymphoma and 14th most common cancer overall in United States.[4][2][3] Males are more commonly affected with multiple myeloma than females; the male to female ratio is approximately 1.54 to 1.[3][5] Multiple myeloma usually affects individuals of the African American and Native Pacific Islanders race. Asian individuals are less likely to develop multiple myeloma.[3] The incidence of multiple myeloma increases with age; the median age at diagnosis is approximately 66–70 years with 37% of patients being younger than 65 years of age.PMID: 28061985

Epidemiology and Demographics

Incidence

  • In 2012, the incidence of multiple myeloma waws approximately 6.3 per 100,000 individuals with a case-fatality rate of 3.3 per 100,000 in the United States.[1]
  • In 2014, multiple myeloma constituted approximately 1.4 percent of the estimated new cancer cases.[6]
  • In 2015, the estimated incidence of multiple myeloma is 1.6% of all new cancer cases and 1.9% of all cancer mortality cases.[2]
  • Multiple myeloma is the 14th leading cause of cancer death in the United States.[2]
  • Since 1975, the overall multiple myeloma incidence has increased nearly 1 percent annually.[6]

Prevalance

  • Myeloma is the 14th leading cause of cancer death in the United States.[2]
  • Multiple myeloma is the second most prevalent blood cancer (10%) after non-Hodgkin's lymphoma.[4][2]
  • There are approximately 76,000 people in the United States living with multiple myeloma.[2]
  • Multiple myeloma represents approximately 1% of all cancers and 2% of all cancer deaths.[3]
  • In 2012, there were an estimated 89,658 people living with multiple myeloma in the United States.[2]

Age

  • The incidence of multiple myeloma increases with age where the median age at diagnosis is is 65 to 70 years. Recent statistics concerning earlier age of onset in multiple myelom indicate an increase in incidence among the population.[7]
  • Multiple myeloma is a common malignancy of patients above 40 years old (70% of cases are diagnosed between 50 and 70 years of age.[5])

Gender

  • Males are more commonly affected with multiple myeloma than females. The male to female ratio is approximately 1.54 to 1.[5]

Race

  • Among African Americans, multiple myeloma is one of the top 10 leading causes of cancer deaths.[2]
  • The incidence of multiple myeloma in the African American population is more than the European American population. PMID: 28061985

Gallery

Multiple myeloma summary.[2]


Percent of new cases by age group: multiple myeloma.[2]


Number of new cases per 100,000 persons by race/ethnicity & sex: multiple myeloma.[2]>


Percent of deaths per age group: multiple myeloma.[2]


Number of deaths per 100,000 persons by race/ethnicity & sex multiple myeloma.[2]


Multiple myeloma percent of total new cancer csases in the United states.[2]


Five year survival percentage.[2]


New cases, deaths, and 5-Year relative survival.[2]

References

  1. ↑ 1.0 1.1 Plasma cell neoplasm.National cancer institute (2015)http://www.cancer.gov/types/myeloma/hp/myeloma-treatment-pdq#cit/section_1.1 Accessed on September, 20th 2015
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  3. ↑ 3.0 3.1 3.2 3.3 3.4 Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015
  4. ↑ 4.0 4.1 Collins, CD. (2005). "Problems monitoring response in multiple myeloma". Cancer Imaging. 5 Spec No A: S119–26. doi:10.1102/1470-7330.2005.0033. PMID 16361127.
  5. ↑ 5.0 5.1 5.2 Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015
  6. ↑ 6.0 6.1 A snapshot of myeloma. National cancer institute(2014)http://www.cancer.gov/research/progress/snapshots/myeloma Accessed on September, 20th 2015
  7. ↑ Press Releases. Compugen (2015)http://www.cgen.com/media-center/press-releases/-314 Accessed on September, 20th 2015

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