Monoclonal gammopathy of undetermined significance x ray

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Omer Kamal, M.D.[3]

Overview

When first evaluating a case of MGUS, a hematologist will usually perform a skeletal survey (X-rays of the entire skeleton) which may show bone lesions. If bony lesions are found, multiple myeloma is more likely diagnosed. If no bony lesions are found, MGUS is still the diagnosis.

X Ray

  • When first evaluating a case of MGUS, a hematologist will usually perform a skeletal survey (X-rays of the entire skeleton) which may show bone lesions.[1][2][3]
    • If bone lesions are found, a diagnosis of multiple myeloma is more likely.
    • If no bone lesions are found, a patient with MGUS is followed up once every 6 months to 1 year with a blood test (serum protein electrophoresis).

References

  1. Jang ST, Sohn IS, Jin ES, Cho JM, Kim CJ, Lim SJ (April 2009). "A case of cardiac dysfunction associated with monoclonal gammopathy of undetermined significance". J. Korean Med. Sci. 24 (2): 354–6. doi:10.3346/jkms.2009.24.2.354. PMC 2672144. PMID 19399286.
  2. Rajan AM, Rajkumar SV (December 2013). "Diagnostic evaluation of monoclonal gammopathy of undetermined significance". Eur. J. Haematol. 91 (6): 561–2. doi:10.1111/ejh.12198. PMID 24033731.
  3. Mangiacavalli S, Cocito F, Pochintesta L, Pascutto C, Ferretti V, Varettoni M, Zappasodi P, Pompa A, Landini B, Cazzola M, Corso A (October 2013). "Monoclonal gammopathy of undetermined significance: a new proposal of workup". Eur. J. Haematol. 91 (4): 356–60. doi:10.1111/ejh.12172. PMID 23859528.

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