Mixed connective tissue disease epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Epidemiology and Demographics
Incidence
- The incidence of mixed connective tissue disease is approximately 2 per 100,000 individuals per year.
Prevalence
- The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
- The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
Mortality rate
- In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
- In MCTD, the mortality rate is nearly 10.4% over the period of 13-15 years.[1]
Age
- Patients of all age groups may develop [disease name].
- The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
- [Disease name] commonly affects individuals younger than/older than [number of years] years of age.
- [Chronic disease name] is usually first diagnosed among [age group].
- [Acute disease name] commonly affects [age group].
Race
- MCTD is more frequent in the black population and among Asians.[2]
- OR
- MCTD is approximately reported in different ethnic groups as follow:
| Prevalence of MCTD according to race | |
|---|---|
| Race | Prevalence (per 100,000 person years) |
| Caucasian | 40 |
| Hispanic | 7.4 |
| African-American | 6.6 |
Gender
- Female are more commonly affected by mixed connective tissue disease than male. The female to male ratio is approximately 5 to 1.[3]
References
- ↑ Ungprasert P, Wannarong T, Panichsillapakit T, Cheungpasitporn W, Thongprayoon C, Ahmed S, Raddatz DA (February 2014). "Cardiac involvement in mixed connective tissue disease: a systematic review". Int. J. Cardiol. 171 (3): 326–30. doi:10.1016/j.ijcard.2013.12.079. PMID 24433611.
- ↑ Missounga L, Ba JI, Nseng Nseng Ondo IR, Nziengui Madjinou M, Malekou D, Mouendou Mouloungui EG, Nzengue EE, Boguikouma JB, Kombila M (2017). "[Mixed connective tissue disease: prevalence and clinical characteristics in African black, study of 7 cases in Gabon and review of the literature]". Pan Afr Med J (in French). 27: 162. doi:10.11604/pamj.2017.27.162.12572. PMC 5567953. PMID 28904690. Vancouver style error: initials (help)
- ↑ Ungprasert P, Crowson CS, Chowdhary VR, Ernste FC, Moder KG, Matteson EL (December 2016). "Epidemiology of Mixed Connective Tissue Disease, 1985-2014: A Population-Based Study". Arthritis Care Res (Hoboken). 68 (12): 1843–1848. doi:10.1002/acr.22872. PMC 5426802. PMID 26946215.