Mitral valve prolapse epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Incidence

Prior to the development of rigorous criteria for the diagnosis and classification of mitral valve prolapse, as described above, the incidence of mitral valve prolapse in the general population varied significantly. Studies estimated the incidence of mitral valve prolapse at 5 to 15 percent or even higher.[1]

Prevalence

As part of the Framingham Heart Study, more modern estimates of the prevalence of mitral valve prolapse have been lower at 2.4%. There was a near-even split between classic and nonclassic MVP, with no significant age or sex discrimination.[2] Based on data gathered in the United States, MVP is prevalent in 7% of autopsies.

References

  1. Levy D, Savage D. (1987). "Prevalence and clinical features of mitral valve prolapse". Am Heart J. 113 (5): 1281–90. PMID 3554946.
  2. Freed LA, Levy D, Levine RA, Larson MG, Evans JC, Fuller DL, Lehman B, Benjamin EJ. (1999). "Prevalence and clinical outcome of mitral-valve prolapse". N Engl J Med. 341 (1): 1–7. PMID 10387935.

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